In the present work, novel 7-aryl-10, 11-dihydro-7H-chromeno [4, 3-b]quinoline-6, 8(9H, 12H)-dione derivatives were synthesized by oxidation of 7-aryl-8, 9, 10, 12-tetrahydro-7H-chromeno[4, 3-b]quinoline-6, 8-diones in the presence of silica sulfuric acid/NaNO2 with yields of 64-74%. Cytotoxic activity of synthesized compounds was assessed on three different human cancer cell lines (K562, LS180...

A green one-pot synthesis of 5H-Chromeno[4,3-b]pyridin-5-one derivatives which are the main core natural product Polyneomarline C is described by reaction 4-chloro-3-formyl coumarin and different cyclic acyclic compounds having active methylene group in presence Et3N NH4OAc EtOH. The advantages this strategy good yields, no need for chromatographic separation absence heavy metal catalysts toxic...

In the first of the compounds reported herein, namely 6'-ferrocenyl-6a'-nitro-6',6a',6b',7',9',11a'-hexa-hydro-2H-spiro-[ace-naphthyl-ene-1,11'-chromeno[3',4':3,4]pyrrolo-[1,2-c]thia-zol]-2-one, [Fe(C5H5)(C29H21N2O4S)], (I), the thia-zolidine ring adopts a twist conformation on the methine N-C atoms. In the second compound, viz. 6'-(4-methoxy-phen-yl)-6a'-nitro-6',6a',6b',7',9',11a'-hexa-hydro-...

Some chromeno[4′,3′-b]pyrano[6,5-b]quinoline derivatives were synthesized by condensation of 2-amino-4-aryl-3-cyano-5-oxo-4H, 5H -pyrano-[3,2-c] chromenes and 1,3-cyclohexanedione in an environmentally benign and efficient method by Cu(II)-Schiff base/SBA-15 as an environmentally friendly heterogeneous and recyclable catalyst under solvent-free conditions in high yields and rates. These kinds o...

ABSTRACT A simple and efficient approach has been developed to synthesise novel functionalised 5H-chromeno[2,3-d] pyrimidines derivatives (4a-h). This entails treating 2-amino-3-cyano-4H-chromenes (3a-h) with formamidine acetate under microwave irradiations solvent-free conditions. All structures of new compounds obtained in this study were characterised by IR, MS, 1H 13C NMR analysis. Addition...

The title compound, C(17)H(15)Br(2)NO(6)S(2)·C(2)H(5)OH, is the esterification reaction product of 2-(8,10-dibromo-2,6-dioxo-3,5,5a,11b-tetra-hydro-2H,6H-chromeno[4',3':4,5]thio-pyrano[2,3-d]thia-zol-5a-yl)acetic acid. Cleavage of the lactone ring and formation of eth-oxy-carbonyl and hy-droxy groups from its structural elements were observed. On the other hand, the carb-oxy-methyl group was no...

A new cyclen derivative L, bearing a methyl-chromeno-pyridinylidene hydrazone moiety, was synthesized and studied in MeOH, as potential fluorescent "OFF-on-ON" sensors for Zn(ii). Photophysical properties of this ligand being PET regulated, L was only weakly emissive in the absence of metal ions (OFF). L fluorescence was increased modestly upon addition of one equivalent of Zn(II), and further ...