نتایج جستجو برای: chromatin remodeling

تعداد نتایج: 94054  

Journal: :Cell 1999
Jessica K Tyler James T Kadonaga

octamer relative to the DNA. The movement of a histone octamer along the DNA must involve the breaking and reestablishment of histone–DNA contacts within the nucleosome, but exactly how the histone–DNA contacts are altered is not known. In theory, the ATP-driven trans-location of a chromatin remodeling complex along the The packaging of the eukaryotic genome into chromatin DNA could directly br...

1999
Jessica K Tyler James T Kadonaga

octamer relative to the DNA. The movement of a histone octamer along the DNA must involve the breaking and reestablishment of histone–DNA contacts within the nucleosome, but exactly how the histone–DNA contacts are altered is not known. In theory, the ATP-driven trans-location of a chromatin remodeling complex along the The packaging of the eukaryotic genome into chromatin DNA could directly br...

Journal: :Molecular and Cellular Biology 2000

Journal: :The International Journal of Developmental Biology 2009

Journal: :Cancer Biology & Therapy 2004

2012
Scott J. Nowak Mary K. Baylies

Embryonic patterning relies upon an exquisitely timed program of gene regulation. While the regulation of this process via the action of transcription factor networks is well understood, new lines of study have highlighted the importance of a concurrently regulated program of chromatin remodeling during development. Chromatin remodeling refers to the manipulation of the chromatin architecture t...

Journal: :Molecular biology of the cell 2008
Thomas A Johnson Cem Elbi Bhavin S Parekh Gordon L Hager Sam John

Brahma (BRM) and Brahma-related gene 1 (BRG1) are the ATP-dependent catalytic subunits of the SWI/SNF family of chromatin-remodeling complexes. These complexes are involved in essential processes such as cell cycle, growth, differentiation, and cancer. Using imaging approaches in a cell line that harbors tandem repeats of stably integrated copies of the steroid responsive MMTV-LTR (mouse mammar...

2015
Mariona Nadal-Ribelles Glòria Mas Gonzalo Millán-Zambrano Carme Solé Gustav Ammerer Sebastián Chávez Francesc Posas Eulàlia de Nadal

Chromatin remodeling is essential for proper adaptation to extracellular stimuli. The p38-related Hog1 SAPK is an important regulator of transcription that mediates chromatin remodeling upon stress. Hog1 targets the RSC chromatin remodeling complex to stress-responsive genes and rsc deficient cells display reduced induction of gene expression. Here we show that the absence of H3K4 methylation, ...

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