Trichomonas vaginalis is a globally common sexually transmitted human parasite. Many strains of T. vaginalis from around the world have been described to be resistant to the current drug of choice, metronidazole. However, only a few cases of metronidazole resistance have been reported from Europe. The resistant strains cause prolonged infections which are difficult to treat. T. vaginalis infect...

Trichomonosis, a sexually transmitted infection (STI) caused by the protist Trichomonas vaginalis, has significant public health relevance. The annual incidence is ,8 million women in the United States and 170 million worldwide, with an equal number of infected male partners [1]. Both men and women infected with T. vaginalis are at increased risk for human immunodeficiency virus infection [1]. ...

One hundred and ninety three consecutive pregnant women attending peripheral antenatal clinics attached to Ngwelezana Hospital, Empangeni, Kwa-Zulu, were examined for evidence of sexually transmitted pathogens. The following incidences were found: Trichomonas vaginalis 49.2% (95), Candida spp 38.3% (74), Chlamydia trachomatis 11.4% (22), Gardnerella vaginalis 6.2% (12), Neisseria gonorrhoeae 5....

1.Honigberg, G. and F. Mohn. 1973. An improved method for the isolation of highly polymerized native deoxyribonucleic acid from certain protozoa. J. Protozool. 20:146150. 2.Riley, D.E. and J.N. Krieger. 1992. Rapid and practical DNA isolation from Trichomonas vaginalis and other nuclease-rich protozoa. Mol. Biochem. Parasitol. 51:161164. 3.Rubino, S., R. Muresu, P. Rappelli,, P. Fiori, P. Rizzu...

Trichomonas vaginalis is one of the most common nonviral sexually transmitted human infections and, worldwide, has been linked to increased incidence of human immunodeficiency virus type 1 transmission, preterm delivery, low birth weight, cervical cancer, and vaginitis. The molecular pathways that are important in initiating host inflammatory and immune responses to T. vaginalis are poorly unde...

Vaginal trichomonosis is a highly prevalent infection which has been associated with human immunodeficiency virus acquisition and preterm birth. Culture is the current "gold standard" for diagnosis. As urine-based testing using DNA amplification techniques becomes more widely used for other sexually transmitted diseases (STDs) such as gonorrhea and chlamydia, a similar technique for trichomonos...

Trichomonas vaginalis (T. vaginalis) is one of the most prevalent, non-viral protozoan pathogens and the most common sexually transmitted organism in females, yet it is one of the least investigated infectious agents. An estimate of around 180 million new infections is found worldwide every year[1,2]. The high T. vaginalis prevalence worldwide is concentrated in developing countries and socioec...

Trichomoniasis is a significant sexually transmitted disease (STD) in the spectrum of public health and primary care because of its association with agents such as human immunodeficiency virus and Neisseria gonorrhoeae. However, its true significance may be underestimated due to diagnostic modalities that exhibit poor sensitivity. A total of 1,086 genital specimens from two urban emergency depa...

Human immunodeficiency virus (HIV) infection is a pandemic that affects all parts of the globe. Current treatments fail to cure disease and for this reason there is significant interest in producing a vaccine to prevent HIV transmission, but clinical trials have proved disappointing. For this reason it is important to consider alternative measures to control incidence and prevalence of the dise...