Chlamydiae are important pathogens of a range of birds and animals including sheep, cattle, pigs, cats, goats, koalas, other Australian marsupials, amphibians and reptiles. Recent changes to chlamydial taxonomy has seen the proposal of two genera, Chlamydia/Chlamydophila with nine species – C trachomatis, C muridarum, C suis, C psittaci, C pecorum, C abortus, C caveae, C felis and C pneumoniae ...

The koala, an iconic marsupial native to Australia, is a threatened species in many parts of the country. One major factor in the decline is disease caused by infection with Chlamydia. Current therapeutic strategies to treat chlamydiosis in the koala are limited. This study examines the effectiveness of an inhibitor, JO146, which targets the HtrA serine protease for treatment of C. pecorum and ...

Intracellular Chlamydia (C.) bacteria cause in cattle some acute but rare diseases such as abortion, sporadic bovine encephalomyelitis, kerato-conjunctivitis, pneumonia, enteritis and polyarthritis. More frequent, essentially ubiquitous worldwide, are low-level, asymptomatic chlamydial infections in cattle. We investigated the impact of these naturally acquired infections in a cohort of 51 fema...

Chlamydia (C.) pecorum, an obligate intracellular bacterial species commonly found in ruminants, can also occur pigs. However, its significance as a potential porcine pathogen, or commensal, is still unclear. In previous study (Hoffmann et al. 2015), mixed infections of C. suis and pecorum were detected 14 Swiss fattening pig farms. Using these samples, we aimed to investigate the infection dyn...

Members of the Chlamydiales order are obligate intracellular pathogens causing acute and chronic infectious diseases. Chlamydiaceae are established agents of community- and zoonotically acquired respiratory tract infections, and emerging pathogens among the Chlamydia-related bacteria have been implicated in airway infections. The role of both in airway infections in Africa is underexplored. We ...

Chlamydial infections in pigs are associated with respiratory disease, diarrhea, conjunctivitis and other pathologies. The aim of this study was to define the prevalence of Chlamydiaceae in Swiss fattening pigs by applying sensitive and specific detection methods and to correlate prior antibiotic treatment and farm related factors with differences in prevalence. Conjunctival and fecal swabs wer...

Devastating fires in Australia over 2019–20 decimated native fauna and flora, including koalas. The resulting population bottleneck, combined with significant loss of habitat, increases the vulnerability remaining koala populations to threats which include disease. Chlamydia is one disease causes morbidity mortality predominant pathogenic species, pecorum , severe ocular, urogenital reproductiv...

This paper reviews new findings on ovine chlamydial abortion. Concerning chlamydial taxonomy, with the recent advances due to the analysis of the ribosomal genes, nine genotypic groups were identified separated into two lineages. It also describes the transmission of the disease, the site of entry of the organism and chlamydial shedding by underlying the role of latent infections. Recent result...

Chlamydia are absolute pathogens of humans and animals; despite being rather well recognised, they are still open for discovery. One such discovery is the occurrence of extrachromosomal carriers of genetic information. In prokaryotes, such carriers include plasmids and bacteriophages, which are present only among some Chlamydia species. Plasmids were found exclusively in Chlamydia (C.) trachoma...