BACKGROUND In the field of acupuncture research, the topic of acupoint specificity has received increasing attention, but no unified conclusion has been reached on whether or not acupoint specificity exists. Furthermore, the majority of previous acupuncture neuroimaging studies have been performed using healthy subjects. In this study, patients with migraine were used to investigate acupoint sp...

Background: The incidence of excessive weight gain during pregnancy continues to increase. Our aim was compare outcomes at different trimesters and classification criteria gestational (GWG) examine whether GWG correlated with adverse in the population Southwest China. Methods: In randomized controlled trial Complex Lipids Mothers Babies (CLIMB) conducted Chongqing, China, data from 1273 women a...

Deqi, according to traditional Chinese medicine, is a specific needle sensation during the retention of needles at certain acupoints and is considered to be necessary to produce therapeutic effects from acupuncture. Although some modern researches have showed that Deqi is essential for producing acupuncture analgesia and anesthesia, the data are not enough. It is a paper of a multicenter, rando...

Background Radiofrequency ablation (RFA) has been recommended as the treatment for benign thyroid nodules (BTNs) by some guidelines. However, detailed follow-up instructions function about timing and affected populations after RFA are lacked due to insufficient researches. This 12-month prospective study aimed evaluate incidence risk factors of dysfunction at different time points RFA, especial...

Abstract Objective To assess the prevalence and distribution of HPV genotypes among Chinese Han women, to explore risk high-grade cervical lesions associated with individual hr-HPV genotypes. Methods Genotyping histopathology data from Multi-Center Screening Trial (CHIMUST) its pilot screening trial, 6 regions across mainland China, were re-analyzed. The physician- self-collected samples 10,867...

Abstract Objective To evaluate the accuracy and safety of contrast-enhanced ultrasound (CEUS) guided biopsy in diagnosis radiologically determined pleural based lesions. Method A prospective study was conducted on patients with Patients who met inclusion criteria received by CEUS to obtain specimens, followed histomathological microbiological examinations. After treatment follow-up, surgical th...

Hypofractionated radiotherapy (HFRT) or chemotherapy combined with programmed death-1 (PD-1) blockade has achieved good clinical control in advanced nonsmall cell lung cancer (NSCLC). However, the relative influence of HFRT + PD-1 and chemo-immunotherapy on peripheral memory T subsets NSCLC responders not been evaluated practice. Thirty-nine patients were enrolled. The frequencies naive (Tn; CD...

STUDY DESIGN Previous works suggested that neutralizing intratumoral lactic acidosis combined with glucose deprivation may deliver an effective approach to control tumor. We did a pilot clinical investigation, including a nonrandomized (57 patients with large HCC) and a randomized controlled (20 patients with large HCC) studies. METHODS The patients were treated with transarterial chemoemboli...

UNLABELLED A rapid expansion of HFMD with enterovirus 71 infection outbreaks has occurred and caused deaths in recent years in China, but no vaccine or antiviral drug is currently available for EV71 infection. This study aims to provide treatment programs for HFMD patients. We conducted a randomized, double-blind, controlled trial and evaluated clinical efficacy of therapy with rHuIFN-α1b in HF...

We attempted to investigate cardioprotection of electroacupuncture (EA) for enhanced recovery after surgery on patients undergoing heart valve replacement with cardiopulmonary bypass. Forty-four patients with acquired heart valve replacement were randomly allocated to the EA group or the control group. Patients in the EA group received EA stimulus at bilateral Neiguan (PC6), Ximen (PC4), Shenti...