background: serum trace element alteration has been reported in dilated and ischemic cardiomyopathy. the reports were controversial. we have studied serum zinc level in cardiomyopathy patients in northern province of mazandaran and compared them with healthy volunteers. methods: serum zinc level was measured in 30 ischemic and 18 dilated cardiomyopathy patients against 27 healthy volunteers. it...

Chemotherapy-induced cardiotoxicity is a serious complication that poses a serious threat to life and limits the clinical use of various chemotherapeutic agents, particularly the anthracyclines. Understanding molecular mechanisms of chemotherapy-induced cardiotoxicity is a key to effective preventive strategies and improved chemotherapy regimen. Although no reliable and effective preventive tre...

conclusions in the setting of acute left ventricular function depression in hocm, a comprehensive differential diagnosis should be established. treatment should be based on hemodynamic changes. after recovery, the prognosis is related to hocm. case presentation we present a unique case where tks occurred in a middle-aged male patient with hypertrophic obstructive cardiomyopathy (hocm) without a...

Anthracycline cardiomyopathy is less frequently encountered nowadays, due to the well-recognised dose limitations and cardiac monitoring protocols used by chemotherapy centres. However, it is a condition that will persist due to the sensitivity of some patients to these drugs and the necessity for large doses to be used for certain individuals. We have demonstrated the benefit of angiotensin-co...

introduction dilated cardiomyopathy (dcm) is the leading cause of heart failure and arrhythmia. case presentation a 47-year-old male, diagnosed with dilated cardiomyopathy, died due to heart failure. during the screening of his family members, his 17-year-old daughter and 9-year-old son also had dilated cardiomyopathy. another daughter had died suddenly at the age of 12 years. conclusions we he...

A 69-year-old man had dyspnea followed by slowly progressive proximal leg weakness over 2 years. He had macroglossia (figure 1). Creatine kinase was 1,378 U/L. A deltoid biopsy revealed myopathy, denervation atrophy, and congophilic deposits around perimysial vessels, indicating amyloid (figure 2). Further workup revealed serum monoclonal lambda protein, bone marrow amyloid, and cardiomyopathy....

Cardiotoxicity of anthracycline chemotherapy drugs is one the main interdisciplinary problems in research area cardio-oncology. As known, high antitumor efficacy antibiotics significantly leveled by development disabling and lethal heart lesions. However, pathogenesis toxic disease, as well diagnostic criteria markers anthracycline-induced cardiomyopathy are not fully understood. The article pr...

Background. Exclusion of underlying coronary artery disease (CAD) is essential in the diagnosis of chemotherapy-induced cardiomyopathy. Presence and severity of CAD can also impact the choice of therapy in cancer patients. The value of cardiac computed tomographic angiography (CCTA) in this setting has not been reported. Methods. We collected data on the clinical presentation and indications fo...

Abstract Doxorubicin (DOX)-induced cardiotoxicity in chemotherapy is a major treatment drawback. Clinical trials on the cardioprotective effects of exercise cancer patients have not yet been published. Thus, we conducted systematic review and meta-analysis preclinical studies for to assess efficacy training DOX-induced cardiomyopathy. We included with animal models cardiomyopathy from PubMed, W...