نتایج جستجو برای: chemical protein interactions

تعداد نتایج: 1867707  

قوتی, شاهرخ, میرحسینی, ضیاءالدین, پزشکیان, زهرا,

Background and purpose: Interferon beta-1b recombinant protein is used for reducing the relapse rate and treatment in patients with Multiple sclerosis (MS). In this study, phylogenetic and in silico analysis of interferon beta-1b were conducted by servers and bioinformatics tools to predict its structural potential. Materials and methods: Physiological and physico-chemical characteristics of...

2014
Lei Chen Jing Lu Tao Huang Jun Yin Lai Wei Yu-Dong Cai Lisa F. P. Ng

Hepatitis C virus (HCV) is an infectious virus that can cause serious illnesses. Only a few drugs have been reported to effectively treat hepatitis C. To have greater diversity in drug choice and better treatment options, it is necessary to develop more drugs to treat the infection. However, it is time-consuming and expensive to discover candidate drugs using experimental methods, and computati...

Journal: :Bioinformation 2005
Cui Zhanhua Jacob Gah-Kok Gan Li lei Meena Kishore Sakharkar Pandjassarame Kangueane

Protein dimers are either homodimers (complexation of identical monomers) or heterodimers (complexation of non-identical monomers). These dimers are common in catalysis and regulation. However, the molecular principles of protein dimer interactions are difficult to understand mainly due to the geometrical and chemical characteristics of proteins. Nonetheless, the principles of protein dimer int...

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