Parkinson’s disease (PD) is a neurodegenerative disease characterized by selective loss of dopamine neurons of the substantia nigra pars compacta. The present study is carried out to investigate the effect of acute and chronic administration of aqueous extract of Lawsonia inermis Linn. leaves on haloperidol induced catalepsy in albino mice which is a useful animal model for screening drugs for ...

Lawsonia intracellularis (LI) is an obligate intracellular proteobacteria that causes porcine proliferative enteritis. The disease affects mainly piglets and has an important role in economic losses in the swine breeding chain, chiefly because it is usually hardly noticed swine herds. Being a disease with cosmopolitan distribution it triggers reduction in average daily gain of weight and feed c...

Ileitis, also known as porcine proliferative enteropathy, is an enteric disease of the lower small intestine and occasionally large intestine that can decrease feed intake, reduce growth performance, and increase mortality in swine. The disease is caused by a gram negative microaerophil bacteria called Lawsonia intracellularis, an intracellular parasite of the enterocytes of the intestine (Dufr...

BACKGROUND Lawsonia inermis (Lythraceae) is an ethnomedicinal plant, traditionally known for curing several ailments such as skin diseases, bacterial infections, jaundice, renal lithiases and inflammation etc. The present work deals with assessment of in vitro antioxidant and in vivo hepatoprotective potential of butanolic fraction (But-LI) of Lawsonia inermis L. leaves. METHODS Antioxidant a...

Lawsonia intracellularis has been identified recently as the etiological agent of proliferative enteropathies, which are characterized by intestinal epithelial hyperplasia and associated moderate immune responses. This disease complex has been reported in a broad range of animals, prevalently in pigs, and L. intracellularis has been linked with ulcerative colitis in humans. L. intracellularis i...

Background: Curcumin is yellow pigment of tumeric, and, that is extracted from it lawsonia (2-hydroxy 1,4 naphtoquinon) is a natural product and it is extracted from henna. Ginger is a dried rhizomes gained from a plant called zingiber officinalea, which is extracted from the family of ginger. Material and Methods: This experimental study performed on adult male rats. Acute inflammatory edema ...

Four new lignans, 3',4'-O,O-demethylenehinokinin (1), chamalignolide (2), 8'beta-hydroxyhinokinin (3) and 7beta,8beta-epoxyzuonin A (4), as well as (-)-hinokinin (5), and (-)-zuonin A (6), were isolated from the heartwood of Chamaecyparis obtusa var. formosana. The structures of these lignans were unambiguously determined by spectroscopic methods. And the absolute configuration of 1 was elucida...

Muurola-4,10(14)-dien-3-one (1), 10-O-acetyl-15-oxo-alpha-cadinol (2), 15-hydroxy-alpha-cadinol (3), 4alpha-hydroxy-5beta-ethoxy-epi-cubenol (4), and 4alpha-hydroxy-5beta-acetoxy-epi-cubenol (5), five new bicyclic sesquiterpenes, have been isolated from the heartwood of Chamaecyparis obtusa var. formosana along with the known compounds epi-cubenol, T-cadinol, T-muurolol, delta-cadinol, and alph...

Proliferative enteritis is an enteric disease that affects a variety of animals. The causative agent in swine has been determined to be an obligate intracellular bacterium, Lawsonia intracellularis, related to the sulfate-reducing bacterium Desulfovibrio desulfuricans. The intracellular agents found in the lesions of different animal species are antigenically similar. In addition, strains from ...