Abstract Introduction/Objective Introduction: Cadherin-16 (CDH16), also termed kidney specific cadherin (ksp-cadherin), is a membrane-associated glycoprotein with role in the embryonal development of tubules and thyroid. Downregulation CDH16 RNA was found papillary carcinomas Methods/Case Report Methods: A set tissue microarrays containing 14,978 samples from 149 different tumor types subtypes ...

Breast cancer is the most common form of in women, its share structure all oncological morbidity European region 28%. leading cause cancer-related death women. We analyzed statistical data Ministry Healthcare Ukraine for 2012–2021, National Cancer Registry Ukraine, and Union WHO as well No. 7 “Report on malignant neoplasms”, Poltava. The analysis dynamics from 2012-2021 was carried out. Data en...

BACKGROUNDS Angiomyofibroblastoma (AMFB) is a rare histopathologic finding of the female lower genital tract. This tumor belongs to the group of mesenchymal tumors. Mesenchymal neoplasms of the modified genital skin and mucosa are uncommon. The majority of these lesions are seen in females and, collectively, they form a family of vulvovaginal soft tissue tumors. This family includes fibroepithe...

introduction: choristoma is defined as the presence of cells in abnormal locations due to defects during embryological development. the word choristoma implies a neoplasm; whereas heterotopia refers to a displaced tissue without necessarily being a swelling or a neoplasm. literature contains reports of cartilaginous choristoma in the cervix, endometrium, breast tissue, and oral region.   case r...

  Introduction: Choristoma is defined as the presence of cells in abnormal locations due to defects during embryological development. The word choristoma implies a neoplasm; whereas heterotopia refers to a displaced tissue without necessarily being a swelling or a neoplasm. Literature contains reports of cartilaginous choristoma in the cervix, endometrium, breast tissue, and oral region.   ...

We have reported that a novel tumor-associated antigen (Ag), 22-1-1, was expressed in cancer cells derived mainly from the uterus and ovary [K. Sonoda et al., Cancer (Phila.), 77: 1501-1509, 1996]. The 22-1-1 Ag existed not only in adenocarcinomas but also in squamous cell carcinomas in the uterine cervix. Here, a relationship between tumor progression and invasion and 22-1-1 Ag expression was ...

Over a 30-year period, 17 patients below the age of 35 with invasive squamous carcinoma of the vulva were identified, 8 of whom (47.1%) had “microinvasive” disease. Venereal diseases and condyloma accuminata were not predisposing factors. Immunosuppression was a contributory factor in 2 patients. Although carcinoma in situ was antecedent in only 1 patient, it was an associated lesion in 87.5% o...

Endometrial and cervical cancers are the most prevalent gynecologic neoplasms. While endometrial cancer occurs in older women, cervical cancer is more prevalente in young subjects. The most common clinical manifestation in these two gynecological cancers is vaginal bleeding. In the first case, diagnosis is made based on histological and imaging evaluation of the endometrium, while cervical canc...

Ovarian metastasis was described the first time by Friedrich Ernst Krukenberg in 1896. Even if the historical timeline dates back to sir James Paget who had described the process in 1854 [1]. The tumor was metastazing from gastric cancer. Consequently, all metastatic ovarian cancers had been referred to as Krukenberg tumors [2]. Actually, Krukenberg tumors account for approximately 15% of malig...

as a tumor composed of admixed benign epithelial and malignant nonepithelial components, and this tumor usually develops as a solitary lesion in the uterine corpus (1). These neoplasms can develop in the endometrial tissue as well as in the ectopic foci of endometriosis. Rare extrauterine müllerian adenosarcomas have been reported to arise in the ovary, cervix, vagina, pelvis, bladder and colon...