OBJECTIVE To compare the impact of 1000 micrograms of self-administered vaginal misoprostol versus self-administered vaginal placebo on preoperative cervical ripening after pre-treatment with estradiol vaginal tablets at home in postmenopausal women prior to day-care operative hysteroscopy. DESIGN Randomised double-blind placebo-controlled sequential trial. The boundaries for the sequential t...

Spontaneous delivery through a cervical tear, provoked by prostaglandin-induced uterine contractions, was described in a G2P0 woman with a history of cervical dilatation and uterine curettage. This rare complication with potentially serious maternal-fetal consequences can be predicted by an aberrant cervical response to prostaglandins in parturients with previous cervical interventions.

OBJECTIVE Small local hospitals with inexperiencedpersonnel often have adverse incidence that could be prevented. A good referral system could reduce this unnecessary death rate. The present study was conducted to determine the pregnancy outcomes of cephalopelvic disproportion (CPD) cases that were referred for cesarean section at a tertiary center and presented the predictivefactorsfor adverse...

OBJECTIVES To determine the efficacy of 400 mcg sublingual misoprost as an adjunct to suction evacuation in first trimester pregnancy termination. METHOD(S) During the study period of January2006-June 2007, two hundred twenty-one pregnant women wanting first trimester pregnancy termination were randomised into two groups. In the study group of one hundred twenty-one women, sublingual misopros...

The aim of this study was to evaluate the effectiveness and safety of emergency cervical cerclage in women with advanced cervical dilatation and bulging of fetal membranes. The study included 158 women who underwent emergency cervical cerclage because of cervix dilatation and protruding membranes in mid-trimester at Sun Yat-sen Memorial Hospital of Sun Yat-sen University. Pregnancy outcomes and...

BACKGROUND To evaluate the effects of vaginal misoprostol on cervical dilatation before operative hysteroscopy in pre-menopausal women. METHODS Four groups of 12 women were randomly assigned to receive either placebo or vaginal misoprostol in doses of 200, 400 or 800 micro g 4 h before the surgical procedure. The number of patients was calculated with an alpha = 0.01 and beta =0.20 for a diff...

results there were significant differences between the groups in subjective labor pain scores (except vas 4) (p < 0.001). the duration of the phase one (3 cm dilatation to full dilatation) and phase two (full dilatation to birth) in the acupressure group was shorter than the control group (phase one, 225 min and 320 min, respectively; phase two, 15 min and 20 min, respectively; both p < 0.001)....