Cerebrovascular diseases are conditions caused by problems with brain vasculature, which have a high morbidity and mortality. Aquaporin-4 (AQP4) is the most abundant water channel in the brain and crucial for the formation and resolution of brain edema. Considering brain edema is an important pathophysiological change after stoke, AQP4 is destined to have close relation with cerebrovascular dis...

The affliction known commonly as ’stroke’ is the third most common cause of death in the developed world after cancer and ischemic heart disease (1). It is responsible for a large incidence of physical disabilities, and becomes more frequent with advancing age (2). The US annual incidence of acute cerebrovascular disease (CVD) is 700,000. Nearly 5 million stroke survivors are involved in person...

BACKGROUND AND PURPOSE Acute cerebral ischemia has been described in different diseases of the thyroid gland, and not only as a result of thyrotoxic atrial fibrillation and cardioembolic stroke. The purpose of this review is to summarize the studies on the relationship between thyroid diseases and cerebrovascular diseases, discussing the main findings for overt hyperthyroidism and hypothyroidis...