We report a case of retinal toxoplasmosis that occurred in a patient with acquired immunodeficiency syndrome who had a previous diagnosis of cerebral toxoplasmosis, despite the patient having had a robust immune response to highly active antiretroviral therapy. Clinical decisions about whether to discontinue secondary prophylaxis for opportunistic infections continue to be challenging.

Protozoal infections, though endemic to certain regions, can be seen all around the world, because of the increase in travel and migration. In addition, immunosuppression associated with various conditions, particularly with HIV infection, favors the occurrence of more severe manifestations and failure to respond to treatments. The CNS may be the only affected system; when not, it is often the ...

CASE REPORT We present the case of a 29 year-old man who came to the Emergency Department due to pain in the right eye. There was demonstrated a complete corneal de-epithelialisation. There was no clinical improvement after appropriate treatment, which was complicated by migraine and vomiting. The computerized tomography (CT) scan showed images suggestive of cerebral toxoplasmosis. After the co...

Hospital Physician July 2008 17 T oxoplasma gondii is an obligatory intracellular pathogen that infects a large proportion of the world population and is a well-recognized cause of illness among persons with AIDS.1 T. gondii infection typically is latent and remains asymptomatic in both immunocompetent individuals and HIV-infected patients. However, patients with HIV are at risk for developing ...

Cerebral toxoplasmosis is one of the most treatable opportunistic infections of the central nervous system in patients with the acquired immunodeficiency syndrome (AIDS).l,2 A combination of sulfadiazine and pyrimethamine is the therapy of choice, producing a favorable clinical response in 68 to 95 percent of patients receiving this regimen.3,4 Reports of sulfadiazine-induced crystalluria and r...

Toxoplasmosis is a disease caused by the intracellular parasite Toxoplasma gondii. Toxoplasmosis is considered one of the most common cerebral opportunistic infections in HIV-AIDS patients. It develops when CD4 count falls below 100 cells/cmm, either from acute exposure to the parasite or from reactivation of latent infection. These patients may also develop extra-cerebral toxoplasmosis such as...

OBJECTIVES To compare the results of magnetic resonance imaging (MRI) and thallium-201 (201Tl) SPET scanning with laboratory analyses including CSF DNA detection, brain biopsy, and necropsy in the discrimination of cerebral lymphoma and toxoplasmosis in patients with AIDS. METHODS A retrospective study of 32 patients infected with HIV who had focal CNS lesions on MRI as a result of either lym...

The research paper deals with the comparison of seroprevalence rate of toxoplasmosis in Ukraine, India and Ghana. It determined that Ukrainian women of reproductive age contaminated with T.gondii. That fact confirmed by the 81,3 % seroprevalence rate with the predomination women living in the rural regions – 87,3±0,58 % comparatively with 71,4±1,11 % urban inhabitants. The rate of seropositive ...

La toxoplasmosis cerebral o neurotoxoplasmosis es una de las infecciones por agentes oportunistas más frecuentes en pacientes infectados virus inmunodeficiencia humana (VIH) y se relaciona con severa. En estos causa lesiones neurológicas alto grado e incluso la muerte. Suele aparecer como múltiples focos lesión predominio gangliobasal realce anular. Se presenta un caso clínico paciente VIH patr...

Toxoplasmosis is a relatively rare complication in renal transplant patients and can pose diagnostic challenges, especially when it manifests as an ocular inflammation. Authors hereby report an unusual case of a 57-year-old male who developed retinochoroidal toxoplasmosis after 15 years of renal transplant, the diagnoses of which were challenging as the patient was also a known case of cerebral...