The present study was oriented towards microencapsulation of aspirin and the study of its release kinetics. The desired encapsulation was achieved by emulsion solvent evaporation method using ethyl cellulose (EC), cellulose acetate phthalate (CAP) and their mixture (1:1) of polymeric constituents. Characterization of the formulations was performed by size, shape, drug loading efficiency and in-...

fe3o4 nanoparticles were synthesizedviaa simple chemical reaction between fecl2.4h2o and fe(no3)3.9h2o under nitrogen atmosphere at room temperature, and then nanoparticles were added to cellulose acetate (ca) polymer. the influence of nanoparticles on the thermal properties of ca polymeric matrix was studied using thermogravimetric analysis (tga). nanostructures were characterized by x-ray dif...

A new oral drug delivery system was developed utilizing both the concepts of controlled release and mucoadhesiveness, in order to obtain a unique drug delivery system which could remain in stomach and control the drug release for longer period of time. Captopril microcapsules were prepared with a coat consisting of alginate and a mucoadhesive polymer such as hydroxy propyl methyl cellulose, car...

The aim of the present study was to develop a new theophylline hard gelatin capsule drug delivery formulation. The formulation have been prepared to enhance its dissolution which could provide better oral absorption of theophylline. Therefore, the effects of the component nature and their proportion in the release rate were investigated. Extended release capsules of theophylline were prepared b...

Introduction: Di (2-ethylhexyl) phthalate is one of the most abundant phthalate esters and it is widely used as softeners in plastic products. Malformation, carcinogenicity, the poisoning of the reproductive system, and also the disruption of the human endocrine system are the harmful effects of these substances. Materials and Methods: In this research, the removal of di (2-ethylhexyl) phthal...

The present study was an attempt to formulate and evaluate enteric coated tablets for esomeprazole magnesium trihydrate. Different core tablets were prepared and formulation (F-1) was selected for further enteric coating, based on the disintegration time. Seal coating was applied to achieve 3% weight gain using opadry®. Enteric coating was carried out using different polymers like Eudragit L-30...

Since oral bioavailability of atenolol and metoprolol tartrate is poor, different matrix –type transdermal patches incorporating atenolol and metoprolol tartrate were formulated with an objective to study the effect of polymers on transdermal release of the drugs. The polymers selected were polyvinylpyrrolidone, cellulose acetate phthalate, hydroxypropylmethylcellulose phthalate and ethyl cellu...