context medication non-adherence is a commonly observed problem in the self-administration of treatment, regardless of the disease type. text messaging reminders, as electronic reminders, provide an opportunity to improve medication adherence. in this study, we aimed to provide evidence addressing the question of whether text message reminders were effective in improving patients’ adherence to ...

background: application of adjuvants with microbial origins is a recently highlighted approach in the vaccinology trials. archaeosomes are among these microbial compounds with both adjuvant and liposomal activities and features. methods: in the present study, recombinant hbsag encapsulated into methanobrevibacter smithii (m. smithii) archaeosomes. balb/c mice immunized with this compound and hu...

in the last decade, cellular automata models have been widely used for simulation spatial phenomena; however, exact nature of these models have been lead to various limitations for essential simulation of these phenomena. in this research, traditional cellular automata models have been developed through fuzzy theory, in which, transition rules are expressed based on fuzzy logic control methodol...

conclusions mobile phone text messaging increased adherence to diabetes therapy and improved the clinical outcome in saudi patients with type 2 diabetes. results in addition to significant improvement in patients’ knowledge, mean fasting blood glucose level improved from 8.60 ± 3.16 to 7.77 ± 3.11 mmol/l and mean hba1c decreased from 9.9% ± 1.8% to 9.5% ± 1.7%. objectives we conducted a study t...

sulfur mustard (sm, bis- (2-chloroethyl) sulphide) is a chemical warfare agent that causes dna alkylation, protein modification and membrane damage. sm can trigger several molecular pathways involved in inflammation and oxidative stress, which cause cell necrosis and apoptosis, and loss of cells integrity and function. epigenetic regulation of gene expression is a growing research topic and is ...

introduction: spatial dose distribution around the radionuclides sources is required for optimized treatment planning in radioimmunotherapy. at present, the main source of data for cellular dosimetry is the s-values provided by mird. however, the mird s-values have been calculated based on analytical formula in which no electrons straggling is taken to account. in this study, we used geant4-dna...

in eukaryotes, vesicle trafficking is regulated by the small monomeric gtpases of the rab protein family. rab11, (a subfamily of the ypt/rab gene family) an evolutionarily conserved, ubiquitously expressed subfamily of small monomeric rab gtpases, has been implicated in regulating vesicular trafficking through the recycling of endosomal compartment. in an earlier communication, we have shown th...

cellular manufacturing system (cms) is highly important in modern manufacturing methods. given the ever increasing market competition in terms of time and cost of manufacturing, we need models to decrease the cost and time of manufacturing. in this study, cms is considered in condition of dynamic demand in each period. the model is developed for facing dynamic demand that increases the cost of ...