نتایج جستجو برای: cel 7a

تعداد نتایج: 4453  

2017
Lihong Niu Xiaohua Sun Juming Tang Jing Wang Barbara A. Rasco Keqiang Lai Yiqun Huang

Ne-Carboxymethyllysine (CML) and Ne-carboxyethyllysine (CEL) are typical advanced glycation endproducts (AGEs) found in foods, which have been linked to various health risks. Little is known about AGEs formation in fish muscle and the variability in AGEs formation from one animal to another. In this study, free CML and CEL (glycated amino acids) and their protein-bound forms (protein glycation ...

Journal: :Journal of lipid research 1991
K Reue J Zambaux H Wong G Lee T H Leete M Ronk J E Shively B Sternby B Borgström D Ameis

We report the isolation and nucleotide sequence of the cDNA for carboxyl ester lipase (CEL) from human pancreas. CEL was purified from human pancreas and microsequence analysis was performed on the amino-terminal and internal peptides. Peptide sequence was used to design oligonucleotide probes for screening a human pancreas cDNA library. Partial length cDNAs for CEL were isolated from the libra...

2017
Malcolm D. Mason Noel W. Clarke Nicholas D. James David P. Dearnaley Melissa R. Spears Alastair W.S. Ritchie Gerhardt Attard William Cross Rob J. Jones Christopher C. Parker J. Martin Russell George N. Thalmann Francesca Schiavone Estelle Cassoly David Matheson Robin Millman Cyrill A. Rentsch Jim Barber Clare Gilson Azman Ibrahim John Logue Anna Lydon Ashok D. Nikapota Joe M. O’Sullivan Emilio Porfiri Andrew Protheroe Narayanan Nair Srihari David Tsang John Wagstaff Jan Wallace Catherine Walmsley Mahesh K.B. Parmar Matthew R. Sydes

Purpose Systemic Therapy for Advanced or Metastatic Prostate Cancer: Evaluation of Drug Efficacy is a randomized controlled trial using a multiarm, multistage, platform design. It recruits men with high-risk, locally advanced or metastatic prostate cancer who were initiating long-term hormone therapy. We report survival data for two celecoxib (Cel)-containing comparisons, which stopped accrual ...

2015
Hervé Pageon Hélène Zucchi Zhenyu Dai David R. Sell Christopher M. Strauch Vincent M. Monnier Daniel Asselineau

Advanced glycation end products (AGEs) accumulate in the aging skin. To understand the biological effects of individual AGEs, skin reconstructed with collagen selectively enriched with N(ɛ)-(carboxymethyl)-lysine (CML), N(ɛ)-(carboxyethyl)-lysine (CEL), methylglyoxal hydroimidazolone (MG-H1), or pentosidine was studied. Immunohistochemistry revealed increased expression of α6 integrin at the de...

Journal: :The Journal of biological chemistry 2003
Toshimitsu Takagi Amy K Walker Chika Sawa Felix Diehn Yasutaka Takase T Keith Blackwell Stephen Buratowski

Eukaryotic mRNA capping enzymes are bifunctional, carrying both RNA triphosphatase (RTPase) and guanylyltransferase (GTase) activities. The Caenorhabditis elegans CEL-1 capping enzyme consists of an N-terminal region with RTPase activity and a C-terminal region that resembles known GTases, However, CEL-1 has not previously been shown to have GTase activity. Cloning of the cel-1 cDNA shows that ...

2017
Stephane Esnault Elizabeth E. Torr Ksenija Bernau Mats W. Johansson Elizabeth A. Kelly Nathan Sandbo Nizar N. Jarjour

Semaphorin-7A is a glycosylphosphatidylinositol-anchored protein, initially characterized as an axon guidance protein. Semaphorin-7A also contributes to immune cell regulation and may be an essential pro-fibrotic factor when expressed by non-fibroblast cell types (exogenous). In mouse models, semaphorin-7A was shown to be important for TGF-ß1-induced pulmonary fibrosis characterized by myofibro...

Journal: :Journal of neurophysiology 2012
Taiju Amano Alon Amir Sonal Goswami Denis Paré

Recent findings implicate the central lateral amygdala (CeL) in conditioned fear. Indeed, CeL contains neurons exhibiting positive (CeL-On) or negative (CeL-Off) responses to fear-inducing conditioned stimuli (CSs). In mice, these cells differ in their expression of protein kinase Cδ (PKCδ) and physiological properties. CeL-Off cells are PKCδ(+) and late firing (LF), whereas CeL-On cells are PK...

2008
George R. Clark Warren R. Roper Deborah M. Tonei L. James Wright

The crystal structure of the title compound, [Ru(C(12)H(12)O(6))(C(18)H(15)P)(2)(CO)], confirms its formulation as a ruthenabenzofuran, with a slightly distorted octa-hedral coordination environment at the Ru(II) ion, and mutually trans triphenyl-phosphine ligands. The metallabicyclic ring system is essentially planar (maximum deviation 0.059 Å).

Journal: :The Biochemical journal 2002
Sara H M Bengtsson Katja Madeyski-Bengtson Jeanette Nilsson Gunnar Bjursell

The bile salt-stimulated carboxyl ester lipase (CEL) is important for the digestion and absorption of dietary lipids, and is expressed at high levels by the exocrine pancreas and the lactating mammary gland. However, the presence of CEL in human plasma suggests that the role of CEL in lipid metabolism may stretch beyond its function in the intestinal lumen, and possibly include interactions wit...

2018
Xiao Chen Hailing Wang Kui Jia Hao Wang Tao Ren

Pulmonary inflammation is a primary characteristic of lung injury initiated by the accession of immune cells into the alveolar space. Neutrophil migration serves an important role in pulmonary inflammation mediated by the migration of neutrophils into hypoxic tissue sites. The elimination of pulmonary inflammation is directly associated with rehabilitation in patients with lung injury. Anti-inf...

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