Ceftizoxime is the standard agent used in prophylaxis of infections after abdominal hysterectomy. Metronidazole could be used instead of ceftizoxime for this matter. To compare these two drugs, in a randomized clinical trial, 34 patients received metronidazole suppositories (1g) and 34 patients received intravenous ceftizoxime (1g) before surgery.   There were not any significant demograp...

We tested a phenyl mannitol broth containing ceftizoxime and aztreonam (PHMB(+)) for detection of methicillin-resistant Staphylococcus aureus (MRSA) with reference MRSA strains and, subsequently, with clinical samples (n = 1,098). All reference MRSA strains induced color change in PHMB(+) after 24 to 72 h of incubation. In a clinical setting, 40 MRSA strains were detected with PHMB(+), compared...

We compared the inoculum effects for 109 recent clinical isolates of the Bacteroides fragilis group of cefoxitin, cefotetan, ceftizoxime, ceftriaxone, and three beta-lactamase inhibitors (clavulanic acid, sulbactam, and tazobactam) and their penicillin-derived components. Bactericidal activity was assayed and morphologic changes were monitored for selected strains exhibiting a large inoculum ef...

The in vitro activities of a new quinolone, WIN 57273, and the combination of piperacillin and tazobactam, a beta-lactamase inhibitor, were compared with those of cefoxitin, ceftizoxime, chloramphenicol, clindamycin, imipenem, metronidazole, and piperacillin for 123 clinical anaerobic isolates. Ceftizoxime and cefoxitin had equivalent activities, while metronidazole was active against gram-nega...

The aim of this study was to determine the prevalence of Salmonella in the urine of UTI patient. Salmonella species are a rare cause of urinary tract infections and it also associated with food-borne gastroenteritis. Salmonella UTI is uncommon and is reported more often in patients with a predisposing factor, such as immune deficiency or a structural abnormality. Total 100 samples of urine were...

ceftizoxime is the standard agent used in prophylaxis of infections after abdominal hysterectomy. metronidazole could be used instead of ceftizoxime for this matter. to compare these two drugs, in a randomized clinical trial, 34 patients received metronidazole suppositories (1g) and 34 patients received intravenous ceftizoxime (1g) before surgery.   there were not any significant demographic (a...

In this study, disk diffusion testing with ceftizoxime and cefuroxime was evaluated for use in predicting the susceptibility of Streptococcus pneumoniae to ceftriaxone and cefotaxime. Of the 194 isolates included in this study, 138 were susceptible, 34 were intermediate, and 22 were resistant to cefotaxime by MIC testing; 138 isolates were susceptible, 35 were intermediate, and 21 were resistan...

A new mouse model of anaerobic infection with Bacteroides fragilis alone or in a mixed infection with Escherichia coli is described. It is established by implantation under the skin of a filter paper disk saturated with the appropriate bacterial suspension. The penetration of antibiotics into the implantation site can be detected by assaying the disk. The local infection can be both standardize...