نتایج جستجو برای: cd8
تعداد نتایج: 39269 فیلتر نتایج به سال:
Behcet disease (BD) is a systemic inflammatory disease of the unknown etiology. There is however, some evidence to suggest that immunological abnormalities are important in its pathogenesis, furthermore several T-cell abnormalities which may be quite relevant to autoimmune origin of the disease have been described. We report here our study of T-cell subsets, B and NK cells in 68 patients with B...
Background : Intravenous immunoglobulin (IVIG) is a plasma derived product. IVIG has been used in treatment of autoimmune, immunodeficiency and infectious diseases. In this study we assessed the effect of intravenous immunoglobulin administration on WBC, neutrophil, lymphocyte and platelet counts as well as the percent of CD4 and CD8 T-cell lymphocytes and number of lymphocytes in pediatric...
Background: Lymphocyte subsets enumeration is considered prominent in the management of primary and acquired immunodeficiency disorders. Because of local variations due to race, age, gender, and environmental conditions on lymphocyte subsets, and to improve the accuracy of interpretation of laboratory findings, reference intervals must be determined in every population. Objective: To establish ...
It has been suggested that prolonged exposure to ionizing radiation may induce immune alteration which may facilitate the development of cancer. However, over the past decades some scientists have reported that low-dose of ionizing radiation is not only a harmless agent but often is benefical. The aim of this study was to evaluate the effects of occupational exposure to low levels of io...
Background: Multiple myeloma (MM) is a malignant plasma cell proliferative disorder with limited immunotherapy treatment because of T cell dysfunction. Objective: To investigate the immunomodulatory function of bone marrow mesenchymal stromal cells (MM-BMSCs) on CD8+ T cells. Methods: Proliferation and cytotoxicity were detected by c...
BACKGROUNDS: Seminoma is frequently observed in human and canine testes especially in cryptorchids. Canine and human seminomas are typically associated with leukocytic infiltration. OBJECTIVES: We aimed to identify the type of lymphocytes that infiltrate to seminomas. METHODS: Tumor infiltrating lymphocytes were evaluated by immunohistological techniques in 5 dogs with diffuse seminoma. Routine...
Background: Azathioprine is an immunosuppressive agent that is used in a variety of dermatologic, digestive and hematologic disorders in both humans and small animals. Aims: The effects of long term Azathioprine administration on complete blood count, rate of CD4+ and CD8+ lymphocytes, serum immunoglobulins and protein concentrations of mixed-breed dogs were evaluated in this study. Methods: 24...
Introduction & Objective: Thalassemia is the most common genetic disorders in the world. These disorders are common in the Middle Estern countries containing Iran. It seems that factors like splenectomy, iron overload, frequent contacts with antigens during blood transfusion & using chelating agents cause severe disturbances to immune system. This study is done to evaluate the immune status ...
behcet disease (bd) is a systemic inflammatory disease of the unknown etiology. there is however, some evidence to suggest that immunological abnormalities are important in its pathogenesis, furthermore several t-cell abnormalities which may be quite relevant to autoimmune origin of the disease have been described. we report here our study of t-cell subsets, b and nk cells in 68 patients with b...
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