Although most patients with chronic myeloid leukemia (CML) treated with imatinib mesylate achieve a complete cytogenetic response (CCR), some patients will relapse. To determine the potential of real-time quantitative BCR-ABL reverse transcriptase-polymerase chain reaction (RT-PCR) to predict the duration of continued CCR, we monitored 85 patients treated with imatinib mesylate who achieved a C...

Objective: To investigate the effects of a 12 week comprehensive cardiac rehabilitation (CCR) programme on patients who have undergone implantation of an implantable cardioverter-defibrillator (ICD). Design: Sixteen patients with ICDs (14 (88%) male, mean (SD) age 58 (10) years, range 34–74 years) were randomised to either attend an individually tailored CCR programme or receive usual care. The...

Introducción: Las enfermedades crónicas, y en particular el cáncer colorrectal (CCR), devienen una experiencia de vida crítica, pues la enfermedad invade desarticula las esferas cotidianidad identidad tanto persona como familia quien lo sufre. Objetivos: Comprender los significados vivida por personas con diagnóstico CCR su cotidiana relación atención salud recibida. Metodología: Se realizó un ...

A new staging system for multiple myeloma (MM) has utilized serum concentrations of beta2-microglobulin (Sbeta2M) and albumin as important prognostic factors for survival. Since Sbeta2M is an indicator of glomerular filtration rate, we compared the prognostic values of Sbeta2M and 24-hr urinary creatinine clearance (Ccr) in patients with MM. We retrospectively reviewed the records of 170 MM pat...

In the past, many production-scheduling methods were developed to achieve high due-date and short manufacturing lead times performance. Among them, DRUMBUFFER-ROPE (DBR) has been recognized as one of the excellent solutions. However, there are some implementation constraints (e.g., time buffer determination, setup ratio evaluation, non-CCR subordination etc.) limit its implementation performanc...

Vismodegib (GDC-0449), an orally bioavailable small-molecule inhibitor of Hedgehog signaling, was recently approved by the U.S. Food and Drug Administration for the treatment of basal cell carcinoma that is either metastatic or locally advanced in patients who are not candidates for surgical resection or radiation. Given the absence of previously defined effective drug therapy for this disease,...

in this study, cross linked chitosan resin (ccr) was prepared by cross linking chitosan with glutaraldehyde, and then î±-ketoglutaric acid-modified chitosan resin (kcr) was obtained by modifying ccr with î±-ketoglutaric acid. the sorption behavior of methylene blue (mb) on kcr and ccr from aqueous solution was investigated. the effect of various experimental parameters (e.g. initial ph, sorbent...

Background: Gastric cancer patients usually suffer from skeletal muscle depletion. The serum creatinine/cystatin C ratio (CCR) is a new, simple tool that could serve as biomarker of mass. This study explored the ability preoperative CCR to predict postoperative complications in with gastric cancer.