نتایج جستجو برای: ccl22

تعداد نتایج: 1448  

2015
Teemu Mäntylä Outi Mantere Tuukka T. Raij Tuula Kieseppä Hanna Laitinen Jaana Leiviskä Minna Torniainen Lauri Tuominen Outi Vaarala Jaana Suvisaari

First-episode psychosis (FEP) is associated with inflammatory and brain structural changes, but few studies have investigated whether systemic inflammation associates with brain structural changes in FEP. Thirty-seven FEP patients (median 27 days on antipsychotic medication), and 19 matched controls were recruited. Serum levels of 38 chemokines and cytokines, and cardiovascular risk markers wer...

Journal: :Iranian journal of immunology : IJI 2012
Nasrollah Erfani Faezeh Moghaddasi-Sani Mahboubeh Razmkhah Mohammad Reza Haghshenas Abdolrasoul Talei Abbas Ghaderi

BACKGROUND CCL22/MDC is a CC chemokine with a critical role in regulation of the immune balance in physiological condition. CCL22/CCR-4 ligation has been documented to participate in the migration of regulatory T (Treg) cells and Th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. OBJECTIVE To investigate the association of a single...

Journal: :iranian journal of medical sciences 0
nasrollah erfani shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran ahmadi-sina nedaei ahmadi student research committee, school of medicine, shiraz university of medical sciences, shiraz, iran mohammad ali ghayumi department of internal medicine, faghihi hospital, shiraz university of medical sciences, shiraz, iran zahra mojtahedi shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz, iran

background: an association between lung cancer and chemokines has been advocated in the recent years. this study aims at investigating the association between lung cancer and 16c/a single nucleotide polymorphism (snp) (rs. 4359426) in c-c motif chemokine 22 (ccl22) as well as c1014t snp (rs. 2228428) in c-c chemokine receptor type 4 (ccr4), which serves as the receptor for ccl22. methods: genot...

Journal: :iranian journal of immunology 0
nasrollah erfani cancer immunology research group, shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz faezeh moghaddasi-sani department of biology, faculty of sciences, islamic azad university-science and research branch, tehran mahboubeh razmkhah cancer immunology research group, shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz mohammad reza haghshenas cancer immunology research group, shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz abdolrasoul talaei department of surgery abbas ghaderi cancer immunology research group, shiraz institute for cancer research, school of medicine, shiraz university of medical sciences, shiraz

background: ccl22/mdc is a cc chemokine with a critical role in regulation of the immune balance in physiological condition. ccl22/ccr-4 ligation has been documented to participate in the migration of regulatory t (treg) cells and th2 lymphocytes to the site of breast tumors; circumstances that are known to be associated with poor prognosis. objective: to investigate the association of a single...

Journal: :Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011
T R Abrahamsson M Sandberg Abelius A Forsberg B Björkstén M C Jenmalm

BACKGROUND Analyses of circulating chemokines offer novel tools to investigate the T helper (Th)1/Th2 imbalance in allergic disease in vivo. OBJECTIVE To relate circulating Th1- and Th2-associated chemokines in infancy to allergic disease, sensitization and probiotic supplementation. METHODS Circulating levels of Th1-associated CXC-chemokine ligand (CXCL)9, CXCL10 and CXCL11 and Th2-associa...

2014
Nasrollah Erfani Ahmadi-Sina Nedaei Ahmadi Mohammad Ali Ghayumi Zahra Mojtahedi

BACKGROUND An association between lung cancer and chemokines has been advocated in the recent years. This study aims at investigating the association between lung cancer and 16C/A single nucleotide polymorphism (SNP) (rs. 4359426) in C-C motif chemokine 22 (CCL22) as well as C1014T SNP (rs. 2228428) in C-C chemokine receptor type 4 (CCR4), which serves as the receptor for CCL22. METHODS Genot...

2015
Na-Jin Kang Dong-Hwan Koo Gyeoung-Jin Kang Sang-Chul Han Bang-Won Lee Young-Sang Koh Jin-Won Hyun Nam-Ho Lee Mi-Hee Ko Hee-Kyoung Kang Eun-Sook Yoo

Macrophage-derived chemokine, C-C motif chemokine 22 (MDC/CCL22), is one of the inflammatory chemokines that controls the movement of monocytes, monocyte-derived dendritic cells, and natural killer cells. Serum and skin MDC/CCL22 levels are elevated in atopic dermatitis, which suggests that the chemokines produced from keratinocytes are responsible for attracting inflammatory lymphocytes to the...

Journal: :Molecular medicine 2012
David W Rosenthal James A DeVoti Bettie M Steinberg Allan L Abramson Vincent R Bonagura

Recurrent respiratory papillomatosis (RRP), characterized by the recurrent growth of benign tumors of the respiratory tract, is caused by infection with human papillomavirus (HPV), predominantly types 6 and 11. Surgical removal of these lesions can be required as frequently as every 3 to 4 wks to maintain a patent airway. There is no approved medical treatment for this disease. In this study, w...

Journal: :Journal of immunology 2004
Darran G Cronshaw Charles Owen Zarin Brown Stephen G Ward

Macrophage-derived chemokine (MDC/CC chemokine ligand 22 (CCL22)) mediates its cellular effects principally by binding to its receptor CCR4, and together they constitute a multifunctional chemokine/receptor system with homeostatic and inflammatory roles in the body. We report the CCL22-induced accumulation of phosphatidylinositol-(3,4,5)-trisphosphate (PI(3,4,5)P(3)) in the leukemic T cell line...

2017
Aerken Maolake Kouji Izumi Kazuyoshi Shigehara Ariunbold Natsagdorj Hiroaki Iwamoto Suguru Kadomoto Yuta Takezawa Kazuaki Machioka Kazutaka Narimoto Mikio Namiki Wen-Jye Lin Guzailinuer Wufuer Atsushi Mizokami

Previous studies have found that tumor-associated macrophages (TAMs) promote cancer progression. We previously reported that TAMs promote prostate cancer metastasis via activation of the CCL2-CCR2 axis. The CCR4 (receptor of CCL17 and CCL22) expression level in breast cancer was reported to be associated with lung metastasis. The aim of this study was to elucidate the role of CCR2 and CCR4 in p...

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