Tunneled catheters are widely used for the provision of hemodialysis. Long-term catheter survival is limited by tunneled catheter-related infections (CRI). This study assesses the efficacy of catheter-restricted filling with gentamicin and citrate in preventing CRI in hemodialysis patients. A double-blind randomized study was conducted to compare heparin (5000 U/ml) with gentamicin/citrate (40 ...

BACKGROUND Peritoneal dialysis (PD) is an effective method of renal replacement therapy for end-stage renal disease patients. The PD catheter could be inserted by surgical (open surgery/laparoscopic-assisted) or percutaneous techniques. However, the efficacy of the techniques, including catheter survival and catheter related complications, is still controversial. METHOD The dataset was define...

OBJECTIVE To determine the factors that affect the dwell time of a central venous catheter. BACKGROUND The own immunodeficiency in cancer patient and the collateral effects of their treatment increase the probability of infection and reduce the time of use of a catheter. SUBJECTS Incipient cohort of 306 patients with cancer, with an average age of 59 +/- 14.5 years. INTERVENTIONS Time zer...

BACKGROUND AND OBJECTIVES This retrospective study compared the effectiveness of the timing of the antibiotic locks to clear catheter-related bacteremia in children on chronic hemodialysis. DESIGN, SETTING, PARTICIPANTS, & MEASUREMENTS The early antibiotic lock group received antibiotic locks along with systemic antibiotics from the very beginning of catheter-related bacteremia. The late anti...

BACKGROUND The standard therapy of dialysis catheter-related bacteraemia involves both systemic antibiotics and catheter replacement. We reported recently that instillation of an antibiotic lock (highly concentrated antibiotic solution) into the catheter lumen after dialysis sessions, in conjunction with systemic antibiotics, can successfully treat many episodes of catheter-related bacteraemia ...

BACKGROUND Central venous catheters are frequently needed for the provision of haemodialysis, but their clinical usefulness is severely limited by infectious complications. The risk of such infections can be reduced by topical application of mupirocin to the exit sites of non-cuffed catheters or by the use of tunnelled, cuffed catheters. Whether mupirocin offers any additional protection agains...

Background: The success of peritoneal dialysis (PD) in elderly patients has been reported to be either slightly inferior or equivalent to that of younger patients. The purpose of this study was to evaluate the outcome and suitability of PD in older individuals. Methods: Between January 2005 and December 2007, 67 patients with end-stage renal disease who underwent a surgical PD catheter insertio...

PURPOSE Infection is the leading complication of long-term central venous catheters, and its incidence may vary according to catheter type. The objective of this study was to compare the frequency and probability of infection between two types of long-term intravenous devices. METHODS Retrospective study in 96 onco-hematology patients with partially implanted catheters (n = 55) or completely ...

BACKGROUND Partial replantation (i.e. replacement of the extraperitoneal portion of the catheter with creation of a new subcutaneous tunnel) has been suggested to avoid catheter removal in patients with persistent exit-site/tunnel infection (ESTI). However, published experience with this technique is limited. METHODS Partial replantation was performed on an outpatient basis under local anesth...