Transdermally delivered nitroglycerin (TTS-NTG) through a rate-controlling membrane yields stable blood levels for 24 h. We studied the effect of TTS-NTG (25 mg per 10 cm2) on exercise induced angina in 10 patients with stable angina pectoris, all in NYHA class III, who were not under treatment with other cardiac drugs. In a pre-study exercise test, all patients had angina pectoris and more tha...

uptake of noradrenaline and on the response to sympathetic stimulation of rat heart. Arch Int Pharmacodyn 201: 400-414, 1973 2 3. Starke K: Alpha sympathomimetic inhibition of adrenergic and cholinergic transmission in the rabbit heart. Naunyn Schmiedebergs Arch Pharmacol 274: 18-45. 1972 24. Haggendal J, Johansson B, Jonason J, Ljung B: Correlation between noradrenaline release and effector re...

Human speech communication can be thought of as comprising two channels – the words themselves, and the style in which they are spoken. Each of these channels carries information. Today's most-advanced text-to-speech (TTS) systems such as [1],[2],[3],[4] fall far short of human speech because they offer only a single, fixed style of delivery, independent of the message. In this paper, we descri...

ost discussions of self-regulation have focused on the generic psychological processes that allow people to control their thoughts, emotions, and behaviors-processes that .a~e nonspecific with regard to the action being regulated (Baumeister, Heatherton, & T ce, 1994; Carver & Scheier, 1981; Mischel, 1996). For example, TOTE (test-operatest-exit) and other cybernetic models of self-control (Car...

Today, we can record and store large amounts of single speaker audio data, and also download it from the web. Generally, these data are prosodically rich and can therefore act as excellent candidates for building concatenative text-to-speech (TTS) systems. But transcritpions for these audio data are often not available and automatic transcriptions are error prone. In addition, these audio data ...

Recently, many studies have shown that the Augmented Reality (AR), Automatic Speech Recognition (ASR) and Text-to-Speech Synthesis (TTS) can be used to help people with disabilities. In this paper, we combine these technologies to make a new system, called "ASRAR", for helping deaf people. This system can take a narrator's speech and convert it into a readable text, and show the text directly o...

Supplemental dosing of an opioid is the main treatment suggested to manage breakthrough pain in cancer patients. The intravenous route has been proven to be safe and effective, providing rapid analgesia in patients receiving oral morphine. Transdermal buprenorphine (TTS-BUP) is increasingly used in cancer pain management, but this drug has been labeled as a difficult drug to use in combination ...

Appropriate phoneme durations are essential for high quality speech synthesis. In hidden Markov model-based text-tospeech (HMM-TTS), durations are typically modeled statistically using state duration probability distributions and duration prediction for unseen contexts. Use of rich context features enables synthesis without high-level linguistic knowledge. In this paper we analyze the accuracy ...

OBJECTIVES/HYPOTHESIS To determine the effect of repeated reprocessing of pediatric tracheostomy tubes (TTs) on biofilm formation. STUDY DESIGN In vitro microbiological study. METHODS Pediatric, uncuffed, polyvinyl chloride (PVC) TTs from two different manufacturers (Tracoe Mini and Shiley) were reprocessed mechanically with household detergent and soaked in sodium hypochlorite (bleach). Tw...

We analyse the nature of the optical counterparts of theROSATall-sky survey (RASS)X-ray sources identifiedwith new weak-line T Tauri (WTTS) stars in the Chamaeleon star forming region (SFR). The newWTTS are distributed throughout the whole SFR, while the classical T Tauri stars (CTTS) are found only in the cloud cores. Adopting a distance of 150pc we derive the stellar parameters and place the ...