Our previous study demonstrated that the combination of mannosylated superoxide dismutase (Man-SOD) and succinylated catalase (Suc-CAT), both of which are designed to be targeted to liver nonparenchymal cells, is a promising approach to prevent the initial phase of hepatic ischemia/reperfusion injury induced by occlusion of the portal vein for 30 min followed by a 1-h reperfusion in mice. In th...

The objective of this study is to determine the effect of Cadmium (a heavy metal) on Catalase activity on tissues of liver, kidney and gill of freshwater air breathing Teleost fish (Heteropneustes fossilis). Catalase, a oxido-reductase enzyme play an important role in anti-oxidant defence System which protect animal from oxidative stress. Heteropneustes fossilis (Bloch), a medicinally important...

In order to evaluate low temperature tolerance of five variable somaclones as well as the cv. Peter Pears of gladiolus (Gladiolus grandiflorus Hort.) from which they were originated, catalase (CAT) activity and hydrogen peroxide (H2O2) level were measured. Before carrying out the analyses, vitroplants of these clones were exposed, during 21 days, to 8 8C temperature. In response to the stress g...

Reactive protein cysteine thiolates are instrumental in redox regulation. Oxidants, such as hydrogen peroxide (H2O2), react with thiolates to form oxidative post-translational modifications, enabling physiological redox signaling. Cardiac disease and aging are associated with oxidative stress which can impair redox signaling by altering essential cysteine thiolates. We previously found that car...

Breast cancer is one of the most commonest cancer after the cervical cancer in Indian women. The balance between oxidant and antioxidant has been suggested as an important factor for initiation and progression of breast cancer. The aim of the study is to determine erythrocyte superoxide dismutase (SOD), catalase (CAT) activities as antioxidant enzymes and malondialdehyde (MDA) levels in women h...

To better understand the mechanisms of plant tolerance to high concentration of arsenic, we characterized two antioxidant enzymes, glutathione reductase (GR) and catalase (CAT), in the fronds of Pteris vittata, an arsenic-hyperaccumulating fern, and Pteris ensiformis, an arsenic-sensitive fern. The induction, activation and apparent kinetics of GR and CAT in the plants upon arsenic exposure wer...

The objective of this study was to evaluate effect of different concentrations of catalase in two extenders on motility, viability and lipid peroxidation bull spermatozoa during semen freezing process. Thirty ejaculates collected from ten Holstein bulls were pooled and evaluated at 37 °C. Pool ejaculated was split into two main experimental groups, 1 and 2. In experiment 1, specimen was diluted...

Materials and methods: Classical biochemical methods were used to determine plasma malondialdehyde (MDA), nitric oxide (NO), glutathione peroxidase (GSH-Px), catalase (CAT), superoxide dismutase (SOD), and glutathione (GSH) levels. Enzyme-linked immunosorbent assay was used to determine plasma insulin levels and reverse transcriptasepolymerase chain reaction was used to determine the levels of ...

Down syndrome or trisomy 21 is the single most common genetic cause of mental retardation. It has been postulated that there is oxidative stress in Down syndrome due to over expression of superoxide dismutase 1 (SOD -1) , an antioxidant enzyme which is coded on chromosome 21(21q22.1). The present study included 31 clinically diagnosed children with Down syndrome. The diagnosis of trisomy 21 was...