Adiponectin is an endogenous insulin-sensitizing hormone which has been found to regulate energy metabolism throughout the body, including the heart. However, low levels of adiponectin are found in patients with diabetes, hypertension and cardiovascular diseases. Thus it has been suggested to be an independent predictor for cardiovascular risk. Paradoxically, recent studies have also determined...

BACKGROUND Streptozotocin-induced diabetes (STZ-D) in rats has been associated with carnitine deficiency, bradycardia and left ventricular enlargement. AIM The purpose of this study was to determine whether oral carnitine supplementation would normalize carnitine levels and cardiac function in STZ-D rats. METHODS Wistar rats (48) were made hyperglycemic by STZ at 26 weeks of age. Same age n...

T-cadherin, a special member of cadherin family, expresses with blood circulation involving the heart i.e. CVS. Cadherin is connected healthy conditions an individual and normal functioning cardio-vascular metabolism. T-cadherin mainly associated vascular system human. Previous studies analysed this been unexpressed within fat storing tissues adipose tissue peri-aortic peri-coronary, it present...

Abstract Funding Acknowledgements Type of funding sources: None. Relevance the problem. Anthracycline cardiotoxicity is most unfavorable form due to irreversible complications cardiovascular system caused by anthracyclines during chemotherapy (CT) breast cancer (BC). Despite fact that this type has been studied better than others, problem preventing such remains relevant day. In our study, we s...

Resveratrol (trans-3,5,4’-tri-hydroxic-stilbene) is a stilbenic structure polyphenol, initially isolated from the root of the white hellebore and later from the root of Polygonum cuspidatum, a plant used in traditional Chinese and Japanese medicine. Resveratrol becomes popular only in 1992, when suggested that it could be the reason behind red wine’s cardio-protective effects (the French parado...

Thrombotic thrombocytopenic purpura (TTP) is a rare variant of thrombotic microangiopathy. We report case TTP in Nigerian chronic kidney disease (CKD) patient who was previously on clopidogrel. The features resolved soon after clopidogrel withdrawn. Clopidogrel cardio-protective anti-platelet drug used CKD patients at risk dyspepsia. However, its potential to cause should be recognized and cons...