The synthesis of novel carbohydrate-based polymers allows the structure to be tailored at the monomer level for a specific property and expands the range of available structures beyond those found in nature. Using a controlled anionic polymerization, a new type of carbohydrate polymer is synthesized in which glucose-derived monomers are joined by an α-1,2 amide linkage to give enantiopure poly-...

The studying of enzymatic esterification of carboxylic acids and higher alcohols was performed by esterase Saccharomyces cerevisiae in water-organic medium. Investigation of the enzyme specificity to acetic substrates showed the best result with acetic acid in esterification reactions with ethanol whereas within other carboxylic acids the esterification decreased with acids: hexanoic > pentanoi...

in the present study, four carbon sources were tested for the polyester synthesis of pseudomonas aeruginosa pa01 which is a ubiquitous environmental bacterium and is one of the top three causes of opportunistic human infections. these included linear c8 to c11 carboxylic acids. octanoic acid, nonanoic acid, decanoic acid and undecanoic acid were added to m1 minimal medium to final concentration...

A selective Pd-catalyzed C(3)−H cis-functionalization of piperidine and tetrahydropyran carboxylic acids is achieved using a C(4) aminoquinoline amide auxiliary. High mono- cis-selectivity attained by mesityl acid as an additive. Conditions are developed with significantly lower reaction temperatures (≤50 °C) than other reported heterocycle C(sp3)−H functionalization reactions, which facilitate...

Studies are described on the metabolism and toxicological detection of the phencyclidine-derived designer drug N-(1-phenylcyclohexyl)-3-ethoxypropanamine (PCEPA) in rat urine using gas chromatographic/mass spectrometric techniques. The identified metabolites indicated that PCEPA was metabolized by N-dealkylation, O-deethylation partially followed by oxidation of the resulting alcohol to the cor...

Thermal analysis of acrylonitrile/acrylic acid P(AN/AA) copolymer films containing 5%, 10% and 20% acrylic acid dendrigrafted with citric acid (CA) is examined using differential scanning calorimetry (DSC) with various heating rates, thermogravimetry (TGA) and derivative thermogravimetric analysis (DTG). Also, the effect of carboxylic acid on thermal stabilization of the P(AN/AA) copolymers, wh...

Chemical tests for measurement of blood alcohols are the subject of much interest. particularly in legal cases, and there is a need for quick, simple and reliable assay methods. Likewise. the determinations of carboxylic acids and aldehydes are of importance in various industrial fields, but such assays are difficult to carry out. especially at low concentrations. In the past. alcohols_ have be...

The first chemical investigation of the Mediterranean deep-sea sponge Poecillastra compressa (Bowerbank, 1866) led to the identification of seven new steroidal saponins named poecillastrosides A-G (1-7). All saponins feature an oxidized methyl at C-18 into a primary alcohol or a carboxylic acid. While poecillastrosides A-D (1-4) all contain an exo double bond at C-24 of the side-chain and two o...

Oxidative cyclizations of a variety of heteroatom nucleophiles onto unactivated olefins are catalyzed by palladium(II) and pyridine in the presence of molecular oxygen as the sole stoichiometric oxidant in a nonpolar solvent (toluene). Reactivity studies of a number of N-ligated palladium complexes show that chelating ligands slow the reaction. Nearly identical conditions are applicable to five...