نتایج جستجو برای: carbohydrate sulfotransferase 6 gene chst6
تعداد نتایج: 2014793 فیلتر نتایج به سال:
GlcNAc-6-O-sulfotransferase is involved in formation of 6-sulfo-N -acetyllactosamine-containing structures such as 6-sulfo sialyl Lewis x. We investigated the mode of expression of GlcNAc-6-O-sulfotransferase during postimplantation embryogenesis in the mouse by in situ hybridization. Sulfotransferase mRNA was not detected on embryonic day (E) 6.5, while on E7.5 it was detected in the mesoderm,...
Cell surface glycans play pivotal roles in immune cell trafficking and immunity. Here we present an efficient method for generating anti-carbohydrate monoclonal antibodies (mAbs) using gene-targeted mice and describe critical glycans in lymphocyte homing. We immunized sulfotransferase GlcNAc6ST-1 and GlcNAc6ST-2 doubly deficient mice with sulfotransferase-overexpressing Chinese hamster ovary ce...
Skeletal dysplasias are a group of rare genetic disorders that affect growth and development the skeleton, leading to physical deformities other medical problems. High-throughput genome sequencing technologies have made it easier genotype disorder, but do not always reflect phenotypic outcome. CHST3-related skeletal dysplasia is caused by reduced function carbohydrate sulfotransferase sulfates ...
The HNK-1 carbohydrate, which is recognized by anti-HNK-1 antibody, is well known to be expressed predominantly in the nervous system. The characteristic structural feature of the HNK-1 carbohydrate is 3-sulfo-glucuronyl residues attached to lactosamine structures (Gal beta1-4GlcNAc) on glycoproteins and glycolipids. The biosynthesis of the HNK-1 carbohydrate is regulated mainly by two glucuron...
In this study, we monitored changes in cell wall sulfated galactans the red seaweed Grateloupia imbricata after rapid (48 h) induction of cystocarp maturation and carpospore development by volatile hormone methyl jasmonate (MEJA). Synthesis galactans, carrageenans, which requires UDP galactose, was followed expression analysis genes encoding phosphoglucomutase (PGM), galactose-1-phosphate uridy...
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