Escherichia coli strains of serogroup 0115:K(-):F165 have been associated with septicemia in calves and piglets. These strains express a capsular antigen referred to as K"V165" which inhibits agglutination of the 0 antigen by anti-0115 serum. We used hybrid transposon TnphoA mutants M48, 18b, and 2, and a spontaneous 0-agglutinable mutant, 5131a, to evaluate the role of K"IV165" in the pathogen...

Pathogenic Neisseria meningitidis isolates in most cases express one of five capsular polysaccharide-defined serogroups, i.e., A, B, C, W-135, and Y. The capsular polysaccharides of serogroups W-135 and Y are composed of repetitive disaccharide units of sialic acid linked to galactose and glucose, respectively (1). The capsule polymerases and the encoding genes synF and synG (also referred to a...

ARTICLE INFO ABSTRACT Article history: Received: 2 May 2014 Accepted: 12 August 2014 Available online: 1 December 2014 Pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. As immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. The aim of this study was to molecular identification and de...

In South Africa, serogroup B meningococcal disease is sporadic. The aim of this study was to characterize serogroup B strains causing invasive meningococcal disease (IMD) in South Africa from 2005 to 2008. Isolates, collected through a national, laboratory-based surveillance program for IMD, were characterized by multilocus sequence typing (MLST). Two thousand two hundred thirty-four cases were...

ARTICLE INFO ABSTRACT Article history: Received: 2 May 2014 Accepted: 12 August 2014 Available online: 1 December 2014 Pasteurella multocida is known as one of the main organisms causing pneumonia in sheep. As immunity in pasteurellosis is serogroup specific, identification of prevalent capsular group among endemic areas is essential. The aim of this study was to molecular identification and de...

The functional activities of serum samples from human infants immunized with a glycoconjugate vaccine for Neisseria meningitidis serogroup C were assessed in a complement-mediated antibody-dependent serum bactericidal assay (SBA) and in a neonate rat model of protection from bacteremia. Selective serum samples from individual human infants were combined to make a panel of 11 serum pools to obta...

Pasteurella multocida is among the most important respiratory pathogens of cattle. Outer-membrane protein (OmpH) constitutes an essential bacterial antigen and is well studied in avian bacterial strains. Studies on isolates from cattle with signs of respiratory disease caused by Pasteurella multocida serotypes A and D have not yet been covered in the literature. The objective of this study was ...

Neisseria meningitidis is an important cause of meningococcal disease globally. Sequence type (ST)-11 clonal complex (cc11) is a hypervirulent meningococcal lineage historically associated with serogroup C capsule and is believed to have acquired the W capsule through a C to W capsular switching event. We studied the sequence of capsule gene cluster (cps) and adjoining genomic regions of 524 in...