Abnormal N-heterocyclic carbene (aNHC) adducts of zinc(II) (1) and aluminum(III) (2) were synthesized. The compounds were characterized by NMR spectroscopy and elemental analysis. The solid state structures of these complexes (1 and 2) were determined by single crystal X-ray study. Furthermore, these organozinc and organoaluminum adducts (1 and 2) were tested for the ring opening polymerization...

Intracerebral implantation of biodegradable polymers loaded with cytotoxic or radiosensitising nucleoside analogues is a promising treatment strategy for malignant gliomas, which are currently intractable. The aim of the study was to develop biodegradable polymers containing nucleosides which could be implanted intracerebrally. Methods of synthesis were developed for the copolymers composed of ...

The structural and kinetic studies of polymerization reactions of ε-caprolactone (ε-CL) using (pyrazolylmethyl)pyridine Cu(II) and Zn(II) complexes as initiators is described. Reactions of 2-(3,5-dimethylpyrazol-1-ylmethyl)pyridine (L1) and 2-(3,5-diphenylpyrazol-1-ylmethyl)pyridine (L2) with Zn(Ac)2·2H2O or Cu(Ac)2·2H2O produced the corresponding complexes [Zn(Ac)2(L1)] (1), [Cu(Ac)2(L1)] (2),...

Partially 2,3-O-methylated amyloses efficiently form inclusion complexes with polytetrahydrofuran and poly(epsilon-caprolactone) by simply mixing them in DMSO-H(2)O (1 : 9) solution, in contrast to the case of the parent amylose in which the corresponding inclusion complexes are only slightly formed.

BACKGROUND The use of biodegradable synthetic nerve conduits for the reconstruction of segmental nerve defects has been extensively reported in both animal and human studies, with a majority of studies evaluating sensory nerve recovery. However, few studies have compared these nerve conduits for functional motor recovery. The purpose of this study was to compare three commercially available, sy...

The chiral title compound, C(7)H(12)O(2), a lactone derivative, features a seven-membered ring that adopts a chair conformation. The crystal structure is stabilized by weak C-H⋯O inter-actions occurring in the (100) plane. The absolute configuration was assigned on the basis of the enantioselective synthesis.

Abstract The development of a feasible industrial method for poly(ϵ‐caprolactone) (PCL) preparation is great significant and challenging. bulk ring‐opening polymerization ϵ‐caprolactone (ϵ‐CL) using various organic acid catalysts benzyl alcohol (BnOH) as the initiator was developed. Benzoic (BA) has been proved to be an efficient catalyst ROP ϵ‐CL under mild conditions. conversion PCL 84.7 % op...

introduction: the native inability of nervous system to regenerate, encourage researchers to consider neural tissue engineering as a potential treatment for spinal cord injuries. considering the suitable characteristics of induced pluripotent stem cells (ipscs) for tissue regeneration applications, in this study we investigated the adhesion, viability and proliferation of neural progenitors (de...

Polyhydroxyurethane-graft-poly(ε-caprolactone) copolymers were prepared in bulk by designing a polyhydroxyurethane system with polymer-in-monomer solubility.