Malignant tumors of head and neck carcinomas are the sixth most common type of cancer. Current systemic therapies for cancer show side effects in normal tissues and short-term efficacy due to drug resistance. Consequently, there is much interest in identifying new drugs for cancer treatment. Crocin (an active ingredient of saffron) has been shown to have cytotoxic effects on cancer cell lines. ...

Introduction: Head-and-neck cancer is the sixth most common cancer worldwide with the number of cases consistently increasing in developing countries. Successful development of effective, safe and cost effective nanoprobes for head-and-neck cancer targeting imaging is a big challenge. This study is aimed to develop cysteamine-folate conjugated gold nanoparticles (F-Cys-AuNPs) a...

introduction: head and neck sarcomas involve a group of rare malignant diseases with a high histological variability involving various anatomical sites that can lead to under-reporting of the true incidence of these neoplasms. this study aimed to epidemiologically investigate the occurrence of sarcomas of the head and neck within the past 20 years in yazd, iran (1994– 2014). materials and metho...

The optimal fractionation schedule for radiotherapy of head and neck cancer has been controversial. The objective of this randomized trial was to test the efficacy of hyperfractionation vs. standard fractionation. Patients with squamous cell carcinoma of head and neck organs were randomly assigned to receive radiotherapy delivered with A) standard fractionation at 2 Gy/fraction/day, 5 days...

............................................................................................................................. i LIST OF ORIGINAL PUBLICATIONS ................................................................................ ii CONTENTS ............................................................................................................................iii ABBREVIATIONS........