we describe a patient with newly diagnosed limy cancer. staging was performed with ct and mediastinoscopy. fdg pet scan was performed and confirmed increased metabolic activity in the primary tumor as well as the hilar lymph node. seven months after initial presentation, the patient was found to have two lytic lesions in the pelvis on plain radiograph. hone scan was negative but pet demonstrate...

Objective(s): BONENAVI, a computer-aided diagnostic system, is used in bone scintigraphy. This system provides the artificial neural network (ANN) and bone scan index (BSI) values. ANN is associated with the possibility of bone metastasis, while BSI is related to the amount of bone metastasis. The degree of uptake on bone scintigraphy can be affected by the type of bone metastasis. Therefore, t...

Mestastatic prostate cancer cells (MPCCs) frequently metastasize to bone, which is a “favorite soil” for colonization and proliferation of MPCCs. Prostate cancer bone mestastasis is tightly associated with tumor-induced bone lesions, most commonly caused from the etiological imbalance between osteoblastic bone formation and osteoclastic bone resorption, and from the anti-tumor immune response. ...

Metastasis means the dissemination of the cancer cells from one organ to another which is not directly connected to the primary site. Metastasis has a crucial role in the prognosis of cancer patients. A few theories, different types of cell and several molecular pathways have been proposed to explain the mechanism of metastasis. In this work, the related articles in the limited period of time, ...

normal 0 false false false en-us x-none ar-sa microsoftinternetexplorer4 background: ca 15.3 is elevated in most patients with distant metastatic breast cancer who had prognostic information. the present study was performed to estimate predictive ability of ca 15.3 in assessment of symptomatic metastasis in patients with breast cancer. materials and methods: during five years, 159 primary breas...

back ground and objective:oral cancer is primarily a disease of epithelial origin. the tongue is the most common site of oral cancer. the aim of this study was to determine the frequency of tongue cancer and signs, symptoms, clinical features, and site of lesions in addition to factors affected this cancer.  materials methods and:twenty eight medical records of patients who admitted for tongue...

abstract malignant spermatic cord tumor is rare. spermatic cord metastasis is less common and the prognosis of these patients is poor. here we report a case of unilateral spermatic cord metastasis from advanced gastric cancer. a 57-year-old male underwent total gastrectomy due to advanced gastric cancer. three years later, a painless hard palpable mass in the left inguinal area developed and th...

introduction: insertion or deletion of a guanine in -1607 at promoter region of matrix metalloproteinase-1 enzyme creates two allelic types for this gene in the population: 2g and 1g, respectively. 2g allele contains an extra binding site for ets transcription factors that this may increase the level of gene expression. therefore, aim of this study was investigation of the single guanine insert...

colorectal cancer most commonly metastasizes to the liver and lung. metastatic colon carcinoma (mcc) to the breast is extremely rare. krukenberg tumor is an uncommon metastatic tumor of the ovary. case presentation: a 38 years woman presented with abdominal pain. in evaluation colon cancer was diagnosed at stage 3. folfox chemotherapy was done. after one year she developed krukenberg tumor. few...