BACKGROUND Broadly disseminating and implementing evidence-based psychotherapies with high fidelity, particularly cognitive behavioral therapy (CBT), has proved challenging for many health-care systems, including the Department of Veterans Affairs, especially in primary care settings such as small or remote clinics. A computer-based tool (based on the coordinated anxiety learning and management...

OBJECTIVES To describe the pediatric interview as it is conducted in different practice settings and with children ranging in age from infancy to adolescence, and to identify pediatric history-taking strategies that varied across age groups. PARTICIPANTS AND METHODS A self-administered survey was designed and mailed to a group of pediatricians in the Chicago metropolitan area to assess common...

We study a model where agents experience anger when they see a firm that has displayed insuffi cient concern for their clients’welfare (altruism) makes high profits. Regulation can increase welfare, for example, through fines (even with no changes in prices). Besides the standard channel (effi ciency), regulation affects welfare through 2 channels: (i) regulation calms down existing consumers b...

Genome-wide association studies have identified several loci associated with Alzheimer's disease (AD), including proteins involved in endocytic trafficking such as PICALM/CALM (phosphatidylinositol binding clathrin assembly protein). It is unclear how these loci may contribute to AD pathology. Here we show that CALM modulates autophagy and alters clearance of tau, a protein which is a known aut...

Most studies of meditation have focused on "actual affect" (how people actually feel). We predict that meditation may even more significantly alter "ideal affect" (how people ideally want to feel). As predicted, meditators ideally wanted to feel calm more and excited less than nonmeditators, but the groups did not differ in their actual experience of calm or excited states (Study 1). We ruled o...

Previous findings suggest that cultural factors influence ideal affect (i.e., the affective states that people ideally want to feel). Three studies tested the hypothesis that cultural differences in ideal affect emerge early in life and are acquired through exposure to storybooks. In Study 1, the authors established that consistent with previous findings, European American preschoolers preferre...

AIMS The aim of this study was to develop an evidence-based self-help website, Computer Assisted Learning for the Mind (CALM) designed to improve mental health amongst medical students; and to assess the proportion, demographics and mental health of students who chose to use the site. METHODS All 2nd and 3rd year medical students from one New Zealand university were invited to participate. De...

System performance in multi-agent resource allocation systems can often improve if individual agents reduce their activity. Agents in such systems need a way to modulate their individual behavior in the light of the system’s state, preferably in a way that does not require centralized control. We illustrate the problem of hyperactive agents in two domains related to resource allocation. We desc...