Patients with traumatic brain injury (TBI) and long-bone fractures can show increased callus formation. This effect has already been reproduced in wild-type (wt) mice. However, the mechanisms remain poorly understood. Leptin is significantly increased following TBI, while its role in bone healing remains unclear. The aim of this study was to evaluate fracture healing in leptin-deficient ob/ob m...

BACKGROUND Obtaining dedifferentiated cells (callus) that can regenerate into whole plants is not always feasible for many plant species. Sugar beet is known to be recalcitrant for dedifferentiation and plant regeneration. These difficulties were major obstacles for obtaining transgenic sugar beets through an Agrobacterium-mediated transformation procedure. The sugar beet line 'NK-219mm-O' is a...

Image Processing based computerized expert system has been developed in the context of fracture treatment of patient. The tibia fracture has been taken into account for various possibilities of the cure analysis. Callus formation along with the Patient tenderness jointly signifies the treatment. The concept of fuzzification between the callus formation between fragment of broken bones and other...

Bone fracture healing is processed through multiple stages including the cartilaginous callus formation and its transition to bony callus. FGFR3 negatively regulates chondrogenesis and enhances osteogenesis during skeleton development. We previously found in mice carrying gain-of-function mutation of FGFR3 that FGFR3 delays the healing of un-stabilized fracture that heals mainly through endocho...

Objective: To develop in vitro callus induction in nodal segments of Decalepis hamiltonii and investigate the antioxidant potential of the callus. Methods: In this study, nodal segments of Decalepis were cultured on Murashige and Skoog (MS) medium supplimented with various concentration of 2,4-D for callus induction and later subcultured on various concentration of NAA and BAP. The antioxidant ...

Despite biliary drainage, she had significant cholestasis, ascites, malnutrition, and transient melena. Subsequently she was evaluated for a liver transplantation. A chest X-ray and an abdominal CT scan were obtained with an incidental finding of healing right sixth and seventh lateral rib fractures with callus formation and healing left seventh lateral rib fracture with callus formation (Figur...

INTRODUCTION Fracture repair constitutes the sequence of cell biological events following bone injury and recapitulates the steps of endochondral ossification observed during embryonic skeletal development and growth. Because of the different phases of fracture healing (inflammation, cartilage formation and remodeling) the fracture callus provides an excellent tool for analysis of cartilage and...

This study was undertaken to elucidate the mechanism of biological repair at the tendon-bone junction in a rat model. The stump of the toe flexor tendon was sutured to a drilled hole in the tibia (tendon suture group, n = 23) to investigate healing of the tendon-bone junction both radiologically and histologically. Radiological and histological findings were compared with those observed in a sh...

An efficient procedure has been developed for callus induction and cell suspension cultures of C. saxicola for the first time. Explant selection was carried out among leaf, stem and root to select a suitable type of explants capable of higher callus formation. Leaf explants thus selected showed maximum response to callus induction (67.1%). Modified B5 medium supplemented with 0.5 mg l(-1) 2,4-D...