Ras cheeses were manufactured using aqueous extract of globe artichoke or artichoke flowers (Cynara scolymus) proteinase as coagulant were compared to calf rennet. There were slight differences between chemical composition of cheese made using vegetable coagulants or calf rennet. Cheeses manufactured with artichoke extract as coagulant exhibited higher (p < 0.05) levels of water soluble nitroge...

The surfactant lining the walls of the alveoli in the lungs increases pulmonary compliance and prevents collapse of the lung at the end of expiration. In premature born infants, surfactant deficiency causes problems, and lung surfactant replacements are instilled to facilitate breathing. These pulmonary surfactants, which form complex structured fluid-fluid interfaces, need to spread with great...

Pulmonary lung surfactant is a mixture of surfactants that reduces surface tension during respiration. Perfluorinated surfactants have potential applications for artificial lung surfactant formulations, but the interactions that exist between these compounds and phospholipids in surfactant monolayer mixtures are poorly understood. We report here, for the first time, a detailed thermodynamic and...

The use of exogenous surfactants has been introduced into the therapy of patients of different ages. Much better results have been obtained in the treatment of respiratory distress syndrome with surfactants enriched with surfactant proteins. In the following study we used protein-containing surfactants (survanta and curosurf). The aim of the following study was to determine the localisation of ...

In a healthy lung, the inside surface of respiratory airways is coated with a thin film of lipids and proteins called lung surfactants (LS) which dynamically alter the surface tension and stabilize airways and reduce the work of breathing. Certain clinical events, such as gastric content aspiration, pneumonia, near-drowning, toxic gas inhalation, or chest/lung trauma will trigger lung surfactan...

Background: To evaluate the clinical efficiency of treatment dry eye disease (DED) with ocular pain using deproteinized calf blood extract (DCBE) drops as compared to 0.3% sodium hyaluronate (SH) drops.

The thermodynamics of conventional surfactants, block copolymers and their mixtures in water was described to the light of the enthalpy function. The two methodologies, i.e. the van't Hoff approach and the isothermal calorimetry, used to determine the enthalpy of micellization of pure surfactants and block copolymers were described. The van't Hoff method was critically discussed. The aqueous co...

As anyone who has ever blown bubbles as or with a child knows, if you stop blowing before the sphere is complete, it collapses and disappears. The gas exchange surfaces of our lungs, the alveoli, are also highly curved, thin-walled, moist membranes that are open to the atmosphere. They too, would tend to go poof! and disappear, save for a mixture of phospholipids and proteins that lines the epi...

Surfactant protein B (SP-B) is an essential component of pulmonary surfactant. Synthetic dimeric SP-B(1-25) (SP-B(1-25)), a peptide based on the N-terminal domain of human SP-B, efficiently mimics the functional properties of SP-B. The authors investigated the optimum lipid composition for SP-B(1-25) by comparing the effects of natural lung lavage lipids (NLL), a synthetic equivalent of NLL (sy...

BACKGROUND Currently, a new generation of synthetic pulmonary surfactants is being developed that may eventually replace animal-derived surfactants used in the treatment of respiratory distress syndrome. Enlightened by this, we prepared a synthetic peptide-containing surfactant (Synsurf) consisting of phospholipids and poly-l-lysine electrostatically bonded to poly-l-glutamic acid. Our objectiv...