AIMS To investigate whether increasing the daily baseline of gut calcium can cause a gradual downregulation of the active intestinal transport of calcium via reduced parathyroid hormone (PTH) mediated activation of vitamin D, and to discuss why such a mechanism might prevent calcium oxalate rich stones. To demonstrate the importance of seasonal effects upon the evaluation of such data. METHOD...

PURPOSE Gokhsuradi churna is an ayurvedic formulation, was investigate for antiurolithiatic activity. METHODS Calcium oxalate crystallization was induced by the addition of 0.01M sodium oxalate solutions in synthetic urine and nucleation method. RESULTS The effect of Gokhsuradi Churna exhibited a concentration dependent inhibition of on calcium oxalate crystallization and nucleation. CONC...

1. Freshly voided urine from healthy subjects was pooled and ultrafiltered (10,000 daltons). The ultrafiltrable and the macromolecular portions were preincubated with calcium oxalate, uric acid and sodium urate crystals and the effects on the inhibitory activity of calcium oxalate crystal growth assessed by monitoring the disappearance of [14C]oxalate from the solution. 2. The inhibitory activi...

It is well known that the principal disadvantage of any method for the determination of calcium involving precipitation as calcium oxalate lies in washing the precipitate. The solubility of the precipitate in water or in dilute ammonium hydroxide is appreciable and, in centrifuging, a small amount of calcium oxalate tends to float on the surface of the liquid and is lost in decanting. The satis...

BACKGROUND A patient with cystic fibrosis (CF) and repeated calcium oxalate renal stones prompted us to investigate other children for risk factors for this recognised complication of CF. METHODS Twenty four hour urinary excretion of calcium, oxalate, and glycolate was measured in children with CF and no symptoms of renal tract stones. Normal diet and treatments were continued. RESULTS In 2...

Correlation of the composition of the urinary calculi with urine pH, especially of diurnal variation, and composition of urinary excretion was studied. Urine pH in the patients with uric acid stones was constantly low and urinary pH in the patients with apatite and struvite stones was always high. Diurnal variation was not observed. In patients with pure calcium oxalate stones, however, urinary...

The establishment of new approaches to control chewing insects has been sought not only for direct use in reducing crop loss but also in managing resistance to the pesticides already in use. Engineered formation of calcium oxalate crystals is a potential strategy that could be developed to fulfill both these needs. As a step toward this development, this study investigates the effects of transf...

PURPOSE Urolithiasis is a common urological disorder responsible for serious human affliction and cost to the society with a high recurrence rate. The aim of the present study was to systematically evaluate the phlorotannin rich extract of Sargassum wightii using suitable in vitro and in vivo models to provide scientific evidence for its antilithiatic activity. MATERIALS AND METHODS To explor...

Of 188 (144 renal, 29 bladder, 15 ureteric) stones analysed, 109 (58%) were pure calcium oxalate stones and in 177 (94%) calcium oxalate was the main component. The remaining were of mixed composition containing calcium phosphate, uric acid and calcium hydrogen phosphate. Serum calcium levels in 50 patients with pure calcium oxalate stones were normal. Majority of the cases (76%) came from the ...

Dietary oxalate plays a very important role in the formation of calcium oxalate stones, and dietary intake of calcium may decrease oxalate absorption and its subsequent urinary excretion. The purpose of the present study was to determine the effect on urinary oxalate excretion of an acute oral calcium load, standard milk, or high-calcium low-fat milk followed by a dose of oxalic acid. Male Wist...