نتایج جستجو برای: caffeine endocrine disrupting compounds
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Hormone disruption is a major, underappreciated component of the plant chemical arsenal, and the historical coevolution between hormone-disrupting plants and herbivores will have both increased the susceptibility of carnivores and diversified the sensitivities of herbivores to man-made endocrine disruptors. Here I review diverse evidence of the influence of plant secondary compounds on vertebra...
The presence and distribution of endocrine-disrupting chemicals (EDCs) in the mariculture fish from Pulau Kukup, Johor Malaysia have been studied along with impact on human health. Six different species were collected, due to their high consumption Asian region—especially Malaysia, assess levels EDCs. highest concentration EDCs detected muscle was dexamethasone (2.37–15.84 ng/g) (0.77–13.41 ng/...
There is considerable public, regulatory, and scientific concern regarding human exposure to endocrine-disrupting chemicals, which include compounds that directly modulate steroid hormone receptor pathways (estrogens, antiestrogens, androgens, antiandrogens) and aryl hydrocarbon receptor (AhR) agonists, including 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) and related compounds. Based on quantit...
The transboundary River Ganga serves as a conduit for meltwater from the Himalayas and is major freshwater source two thirds of Indian population before emptying into Sundarban Delta, largest estuary in Bay Bengal. Endocrine disrupting compounds (EDCs) such phthalic acid esters (PAEs) bisphenol A (BPA) used organic plastic additives can pollute aquatic environment receiving litter. Hence, we ha...
There has been a great deal of international discussion on the nature and relevance of endocrine disrupting compounds in the environment. Changes in reproductive organs of fish and mollusks have been demonstrated in rivers downstream of sewage discharges in Europe and in North America, which have been attributed to estrogenic compounds in the effluent. The anatomical and physiological changes i...
Organotin compounds such as triphenyltin (TPT) and tributyltin (TBT) act as endocrine disruptors through the peroxisome proliferator-activated receptor γ (PPARγ) signaling pathway. We recently found that TPT is a particularly strong agonist of PPARγ. To elucidate the mechanism underlying organotin-dependent PPARγ activation, we here analyzed the interactions of PPARγ ligand-binding domain (LBD)...
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