The 5'-untranslated region of the hepatitis C virus (HCV) RNA contains a highly structured motif called IRES (Internal Ribosome Entry Site) responsible for the cap-independent initiation of the viral RNA translation. At first, the IRES binds to the 40S subunit without any initiation factors so that the initiation AUG codon falls into the P site. Here using an original site-directed cross-linkin...

We study the effect of interview modes on estimates of economic inequality which are based on survey data. We exploit variation in interview modes in the Austrian EU-SILC panel, where between 2007 and 2008 the interview mode was switched from personal interviews to telephone interviews for some but not all participants. We combine methods from the program evaluation literature with methods from...

Originally, behavioral law and economics was an exercise in exploring the implications of key findings from behavioral economics (and psychology) for the analysis and reform of legal institutions. Yet as the new discipline matures, it increasingly replaces foreign evidence by fresh evidence, directly targeted to the legal research question. This chapter surveys the key methods: field evidence, ...

General Equilibrium and the Emergence of (Non) Market Clearing Trading Institutions We consider a pure exchange economy, where for each good several trading institutions are available, only one of which is market-clearing. The other feasible trading institutions lead to rationing. To learn on which trading institutions to coordinate, traders follow behavioural rules of thumb that are based on t...

In a previous study, we reported that Alzheimer's disease-associated presenilin-2 interacts with a LIM-domain protein, namely, DRAL/FHL2/SLIM3. In this study, we investigated whether DRAL modifies the metabolism of the amyloid precursor protein (APP). We used small interfering RNA (siRNA) to knockdown DRAL in COS7 and HEK293 cells that stably overexpress APP695. We found that the knockdown was ...

The recent digitization of complete count census data is an extraordinary opportunity for social scientists to create large longitudinal datasets by linking individuals from one another or other sources the census. We evaluate different automated methods record linkage, performing a series comparisons across and against hand linking. have three main findings that lead us conclude perform well. ...

The Ukrainian Longitudinal Monitoring Survey: Towards a Better Understanding of Labor Markets in Transition The paper presents the Ukrainian Longitudinal Monitoring Survey (ULMS), which is one of the most widely used household and labor force surveys in Eastern Europe. It is based on a statistically representative sample of the Ukrainian population aged between 15 and 72 years, comprising about...

The growth hormone receptor contains seven cysteine residues in its extracellular domain. The six in the growth hormone binding domain form disulfide bonds, and help the receptor to gain its correct three-dimensional structure. In this study we replaced the cysteine for serine and alanine residues and investigated their role in growth hormone receptor folding, dimerisation and signal transducti...

This study investigates whether and how the demand for animal-friendly pork can benefit from individual joint use of label “Animal Friendly,” “Organic,” “Local,” “Low Fat.” A choice experiment was conducted to collect data. The data were analyzed using random parameter logit latent class models. Three consumer segments identified. Consumers in Segment 1 (pro-welfare consumers—39% all respondent...