The structure of the side chain of the 3 alpha, 7 alpha, 12 alpha-trihydroxy-5 beta-C29 dicarboxylic bile acid occurring in body fluids of infants with coprostanic acidemia was investigated by means of mass spectrometry and nuclear magnetic resonance spectroscopy. The findings identified this bile acid as 3 alpha, 7 alpha, 12 alpha-trihydroxy-27a, 27b-dihomo-5 beta-cholestane-26,27b-dioic acid ...

Crude oil samples recovered from three oilfields distributed within the central Niger Delta were used to investigate biological marker fingerprints, sources of organic matter, conditions deposition, and thermal maturation. This was achieved by application gas chromatography-mass spectrometric (GC-MS) analyses on saturated components crude oils. The ratios show low sterane/hopane (steranes/hopan...

Two strategies for the projected total synthesis of the phenomenally potent antitumour macrolides amphidinolide N (1) and caribenolide I (2) are described. The title compounds are introduced as challenging and unique targets for chemical synthesis, and their retrosynthetic analysis is presented. The synthesis of the four defined key building blocks (10, 39, 67 and 72), required for the construc...

Surface sediments were collected from various locations of the Mandovi estuary and the Marmugoa harbour. Sediments were analysed for organic carbon (OC), total lipids, n-alkanes concentration and composition. Concentrations of OC, total lipids and n-alkanes varied spatially and ranged from 1 to 2.5%, 176 to 1413 microg/g dry weight (dw) sediments, and 0.8 to 3.2 microg/g dw sediments of the Man...

We here estimate past temperature and hydroclimate variations in eastern Anatolia for marine isotope stages 4 to 1 (MIS4 MIS1) respectively using branched glycerol dialkyl tetraethers (brGDGTs) the hydrogen isotopic composition of n-C29 leaf-wax n-alkanes (?2Hwax) stored sedimentary record Lake Van (Turkey). Our millennial-scale lipid biomarker records reflect warm wet conditions during interst...

Saturated hydrocarbons (SHC) of five cruciferous host plants viz., cabbage, cauliflower, broccoli, knol khol and Brussels sprout and the larvae of diamondback moth (DBM), Plutella xylostella reared on these host plants were identified through gas-chromatography. The hydrocarbon profile of host plants and larval body extract of DBM reared on respective host plants revealed a wide variation in qu...

Saturated hydrocarbons are widely used in the valuation of source rocks and oils, but applicability related parameters has received less attention. Based on thermal simulation experiments Mesozoic Yingen-Ejinaqi Basin, GC-MS analysis saturated hydrocarbon fractions expelled oils extracts from solid residues, to lacustrine oil were discussed. The results indicated that: Controlled by degradation...

We examined, by reverse-phase high performance liquid chromatography (HPLC), the hydrophilic-hydrophobic balance of cholesterol and 12 non-cholesterol sterols and related this property to their equilibrium micellar solubilities in sodium taurocholate and sodium glycodeoxycholate solutions. Sterols investigated exhibited structural variations in the polar function (3 alpha-OH, 3 beta-OH, 3 beta-...