نتایج جستجو برای: c difficile infection
تعداد نتایج: 1464149 فیلتر نتایج به سال:
Prevention of Clostridium difficile infection has become extremely important because of increases in its incidence and severity. Unfortunately, efforts at C. difficile infection prevention are hampered by lack of data to support optimal prevention methods, especially for endemic C. difficile infection. Studies are needed to define the optimal prevention practices and to investigate novel preven...
To the Editor—We read with great interest the recent article by Morrison et al indicating that acid suppression increases mortality in Clostridium difficile infection [1]. The study also showed increased mortality associated with advanced age and corticosteroid use. Acid suppression has been shown to be associated with the risk of C. difficile infection after adjusting for comorbidities [2]. We...
Clostridium difficile is a formidable nosocomial and community-acquired pathogen, causing clinical presentations ranging from asymptomatic colonization to self-limiting diarrhea to toxic megacolon and fulminant colitis. Since the early 2000s, the incidence of C. difficile disease has increased dramatically, and this is thought to be due to the emergence of new strain types. For many years, the ...
The incidence of Clostridium difficile infection is increasing worldwide, and its severity and resulting mortality are also on the rise. Metronidazole and oral vancomycin remain the treatments of choice, but there are concerns about treatment failure and the appearance of resistant strains. Furthermore, antibiotic therapy results in recurrence rates of at least 20%. Fecal transplantation may be...
Abstract Background: Clostridium difficile infection (CDI) has been a major growing problem in hospitals in recent years. Detection of the source of Clostridium difficile strains is of importance for the control of the nosocomial spread of this microorganism. This study was done to identify C.difficile isolates by polymerase chain reaction, (PCR), ribotyping. Materials and methods: The descript...
BACKGROUND The control of Clostridium difficile infections is an international clinical challenge. The incidence of C difficile in England declined by roughly 80% after 2006, following the implementation of national control policies; we tested two hypotheses to investigate their role in this decline. First, if C difficile infection declines in England were driven by reductions in use of particu...
Clostridium difficile infection is increasingly recognized as a cause of diarrhea in outpatients and persons with no apparent health care facility contacts. In contrast to C. difficile infection acquired in health care settings, few risk factors for development of community-associated C. difficile infection are known. Foodborne transmission of C. difficile has been hypothesized as a possible so...
Clostridium difficile colitis has doubled in North America over the past 5 years and recent reports have demonstrated an increase in incidence and severity of these infections in patients with inflammatory bowel disease (IBD; Crohn's disease, ulcerative colitis). Studies from single institutions as well as trends identified in nationwide inpatient databases have shown that IBD patients with con...
BACKGROUND Clostridium difficile is the most common cause of healthcare-acquired infection; the real-world impacts of some proposed C. difficile prevention processes are unknown. METHODS We conducted a population-based retrospective cohort study of all patients admitted to acute care hospitals between April 2011 and March 2012 in Ontario, Canada. Hospital prevention practices were determined ...
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