نتایج جستجو برای: buthus eupeus

تعداد نتایج: 278  

2017
Mohammad Khosravi Mansour Mayahi Farnoosh Kaviani Mohammad Nemati

Background Many elements such as immunosuppressive, chemotactic and anti-inflammatory peptide that could effect on human and animals physiologic system were determined in venom. This study evaluated the use of Mesobuthus eupeus scorpion venom fractions as an immunomodulator. Methods The venom fractions collected from Khuzestan Province in South West of Iran were purified by ion exchange chrom...

Journal: :تحقیقات دامپزشکی 0
فاطمه حسنی نیا گروه علوم دامی، دانشکده علوم دامی و صنایع غذایی دانشگاه کشاورزی و منابع طبیعی رامین خوزستان، خوزستان- ایران محمد تقی بیگی نصیری گروه علوم دامی، دانشکده علوم دامی و صنایع غذایی دانشگاه کشاورزی و منابع طبیعی رامین خوزستان، خوزستان- ایران عباس جلودار گروه علوم پایه، بخش بیوشیمی و مولکولی دانشکده دامپزشکی دانشگاه شهید چمران اهواز، خوزستان- ایران هدایت اله روشنفکر گروه علوم دامی، دانشکده علوم دامی و صنایع غذایی دانشگاه کشاورزی و منابع طبیعی رامین خوزستان، خوزستان- ایران

background: the mesobuthus eupeus scorpion venoms are known to contain α-toxin peptides, many of which interfere with k+ ion channel function. these toxin peptides have important value in  the pharmacology and physiology studies of specific k+ channel of cells. objectives: given the  lack of information of the molecular biology of peptides in the toxin of iranian scorpions, the aim of this stud...

Journal: :archives of razi institute 0
mohammad khosravi department of pathobiology, faculty of veterinary medicine, shahid chamran university of ahvaz, khuzestan, iran mansour mayahi department of clinical sciences, faculty of veterinary medicine, shahid chamran university of ahvaz, khuzestan, iran seyedeh missagh jalali department of clinical sciences, faculty of veterinary medicine, shahid chamran university of ahvaz, khuzestan, iran anahita rezaie department of pathobiology, faculty of veterinary medicine, shahid chamran university of ahvaz, khuzestan, iran ahmad taghavi moghadam razi reference laboratory of scorpion research, razi vaccine and serum research institute, ahvaz, iran zohreh hosseini student of veterinary medicine, faculty of veterinary medicine, shahid chamran university of ahvaz, iran. seyedeh kolsum barzegar

this study aimed to evaluate the clinical, histopathological and hematological effects of mesobuthus eupeus venom on chicken organs. adult chickens were subcutaneously injected with five doses of m. eupeus venom (0.5, 2, 5, 10 and 20 mg/kg; four chickens per each dose). symptoms were recorded during the experiment and blood samples were collected for hematological analysis. moreover, a complete...

Journal: :iranian journal of nuclear medicine 2010
seyed pezhman shirmardi mostafa gandomkar mojtaba shamsaei abbas zare mirakabadi mohammad ghannadi maragheh

introduction: iranian scorpion species are classified in buthidae and scorpionidae with 16 genera and 25 species. in iran, similar to other parts of the world, there are a few known species of scorpions responsible for severe envenoming. mesobuthus eupeus is the most common species in iran. its venom contains several toxin fractions which can affect the ion channel. in this study purification, ...

Journal: :journal of arthropod-borne diseases 0
mehdi khoobdel health research center, baqiyatallah university of medical sciences, tehran, iran. taghi zahraei-salehi department of microbiology, faculty of veterinary medicine, university of tehran, tehran, iran. bahar nayeri-fasaei department of microbiology, faculty of veterinary medicine, university of tehran, tehran, iran. mohammad khosravi health research center, baqiyatallah university of medical sciences, tehran, iran. zahra omidian department of parasitology, faculty of veterinary medicine, university of tehran, tehran, iran. mohammad hassan motedayen razi vaccine and serum research institute-karaj branch, karaj, iran.

b a ckground: scorpions stings are a health problem in many parts of the world. mesobuthus eupeus (buthidae) is the most prevalent species in the middle east and central asia. definition of toxicogenic and immunogenic characteris- tics of the venom is necessary to produce antidote. in this study, the noted properties of m. eupeus venom were eval- uated. m e t hods: venom was obtained by milking...

In this study, Mesobuthus gibbosus and Mesobuthus eupeus eupeus venom samples were compared for lethality, in vivo effects and proteins. Neutralization capacity of monovalent Androctonus crassicauda antivenom (RSHA anti-Ac) was tested against the lethal effects of the venoms.Venom was obtained from mature scorpions by electrical stimulation of the telson. The lethality of the venom and potency ...

Scorpions are generally an important source of bioactive components, including toxins and other small peptides as attractive molecules for new drug development. Mesobuthus eupeus, from medically important and widely distributed Buthidae family, is the most abundant species in Iran. Researchers are interesting on the gland of this scorpion due to the complexity of its venom. Here, we have analyz...

BACKGROUND: Mesobuthus eupeus is an indigenous scorpion species in Southwest Iran which is respon- sible for the majority of scorpion sting cases in Khuzestan province. OBJECTIVES: The effects of M. eupeus venom were investigated on the chief metabolic hormones in rats. METHODS: A total of 45 Albino male rats were ...

Journal: :Protein and peptide letters 2005
Chong Li Wei Liu Frank Bossmans Rong-Huan Zhu Jan Tytgat Da-Cheng Wang

The cDNA of BmK IT-AP, an excitatory insect toxin from the scorpion Buthus martensi Karsch that has an analgesic effect on mammalian cells, was expressed in E. coli in the form of an inclusion body. Following denaturation and reduction, the recombinant protein was renatured and purified by liquid chromatography. The authenticity of the recombinant product was confirmed by bioassay and its elect...

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