1. Yong CS, Jung JH, Rhee JD, Kook KC, Choi HG. Physicochemical characterization and evaluation of buccal adhesive tablets containing omeprazole. Drug Develop Ind Pharm 2001;27:447-55. 2. Martindale-The complete drug reference. In: Sweetman SC, editor. London: Pharmaceutical Press; 2005. 3. Clarke’s Analysis of Drugs and Poisons. In: Moffat AC, Osselton MD, Widdop B, editors. London: Pharmaceut...

PURPOSE The present study involves preparation and evaluation of diclofenac buccal-mucoadhesive microparticles for prolongation of buccal residence time. METHODS The microparticles were prepared by modified double-emulsion dehydration method (O1/W/O2) using sodium carboxymethylcellulose (CMC-Na) as mucoadhesive polymer. Calcium chloride was used as a cross-linking agent. Buccal-mucoadhesive m...

Buccoadhesive buccal delivery systems for isosorbide dinitrate in the form of unidirectional buccal films were developed and characterized for improving bioavailability. The films were formulated by solvent casting method using different bioadhesive polymers like Carbopol 934P and polyvinyl pyrrolidone by using two different plasticizers propylene glycol and diethyl phthalate. Unidirectional re...

Drug delivery via buccal mucosa by means of buccoadhesive formulations offer distinct advantages over peroral administration. Recently, plant gums and exudates have been screened for their use as pharmaceutical adjuvants. The aim of this study is to evaluate matrix tablets containing Plantago psyllium seed mucilage in addition to carbopol as a mucoadhesive agent, and propranolol hydrochloride a...