Brucella spp. are facultative intracellular parasitic pathogens that can survive and multiply in professional and nonprofessional phagocytes. These pathogens are responsible for brucellosis, which can cause abortion in domestic animals and undulant fever in humans. Brucella spp. can survive in a variety of cells and their virulence and chronic infections are thought to be due to their ability t...

AIM To provide an up-to-date overview on the role of Brucella as a possible biological (B-) agent to be used in biological warfare, biological crimes and biological terrorism (with special respect to agroterrorism) scenarios. METHODS An analysis of current literature and of Internet-based sources was made. RESULTS Brucella spp. have always been in the focus of military decision. The main re...

Brucella spp. is a common zoonotic infection referred to as Brucellosis, and it is a serious public health problem around the world. There are currently six classical species (pathogenic species in both animals and humans) within the genus Brucella. The ability and practicality facilitated by a microarray experiment help us to recognize Brucella spp. and its antibiotic resistant gene. Rapid phe...

In the current study, some plants were selected to screen their potential antibacterial activity. For evaluating activity, both aqueous and organic solvents) methanol acetone (were used. The tested Cymbopogon schoenanthus, Cotula cinerea, Francoeuria crispa. Agar well diffusion method was used test activity against two Gram negative (Brucella spp., Proteus spp.) three positive (Staphylococcus a...

A latex coagglutination assay was developed to identify rough (R) isolates of Brucella. Latex beads were coated, via protein A, with either an anti-Brucella rough-lipopolysaccharide (R-LPS) monoclonal antibody (MAb) or an anti-Brucella 25-kDa outer membrane protein (Omp25) MAb. Slide agglutination tests were done for 68 strains of Brucella spp., including type strains of all biovars as well as ...

Brucella spp infections of marine mammals are often asymptomatic but have been associated with reproductive losses and deaths. Zoonotic infections originating from marine isolates have also been described. Hector's dolphins (Cephalorhynchus hectori) are an endangered species with a declining population, and the role of infectious disease in population dynamics is not fully understood. In this s...

Brucellosis caused by Brucella spp. is a major zoonotic disease. Control of brucellosis in agricultural animals is a prerequisite for the prevention of this disease in human beings. Recently, Brucella melitensis was declared by the Centers for Disease Control and Prevention to be one of three major bioterrorist agents due to the expense required for the treatment of human brucellosis patients. ...

Abstract Brucella spp. are facultative intracellular bacterial pathogens that have the ability to survive and multiply in professional nonprofessional phagocytes. Successful invasion chronic persistence indicate manipulates various host cellular processes create a replication permissive niche. The essential mechanisms factors support of remain poorly understood. RNA interference (RNAi) is poten...

INTRODUCTION In previous articles the distribution and diversity of Brucella sp infections has been covered. In addition the evasive mechanisms used by Brucella spp in avoiding the innate and acquired immune systems has been discussed in detail. This article will cover diagnostic tests and recent work on Brucella testing and the possible implications in strategies for diagnosis and control. The...