Broussonetia papyrifera and Lonicera japonica have long been used in the treatment of inflammatory disorders in Chinese medicine, especially respiratory inflammation. Previously, a new phytoformula (BL) containing B. papyrifera and L. japonica was found to exert strong anti-inflammatory activity against several animal models of inflammation, especially against an animal model of acute bronchiti...

Industry 4.0 will upgrade Germany’s industrial capabilities. With trade flows becoming increasingly internationally interlinked, automation, more flexible processes as well as horizontal and vertical integration are becoming more important features in a modern, competitive production structure. Germany in particular with its especially favourable fundamental features will find that “Industry 4....

COST – European Cooperation in Science and Technology – opened up the field of personalized medicine in 1986 when, as part of the Biomedicine and Molecular Biosciences Domain, it sanctioned a research network (aka COST Action) to recruit trial subjects based on differences in metabolic capacity (COST Action B1, 1986). Since then, progress in technology, along with a growing understanding of ind...

AIMS AND OBJECTIVES To examine the literature related to a large-scale quality improvement initiative, the 'Productive Ward: Releasing Time to Care', providing a bibliometric profile that tracks the level of interest and scale of roll-out and adoption, discussing the implications for sustainability. BACKGROUND Productive Ward: Releasing Time to Care (aka Productive Ward) is probably one of th...

The article 'Structure of the nervous system of the nematode Caenorhabditis elegans' (aka 'The mind of a worm') by White et al., published for the first time the complete set of synaptic connections in the nervous system of an animal. The work was carried out as part of a programme to begin to understand how genes determine the structure of a nervous system and how a nervous system creates beha...

Gonorrhea (aka "the clap," or "the drip") is caused by sexually transmitted Neisseria gonorrhoeae--a Gram-negative diplococcus. One of the most common reportable diseases in the United States, gonorrhea frequently affects sexually active adolescents. Approximately 30% of the 350,000 annual cases involve 15to 19-year-olds. (That percentage is thought to be an underestimate!) Those most often inf...

An extract of Humicola fuscoatra (UCSC strain no. 108111A) was shown to reactivate latent HIV-1 expression in an in vitro model of central memory CD4+ T cells. We report the bioassay-guided isolation and structure determination of several resorcyclic acid lactones, including four known compounds, radicicol (1, aka. monorden) and pochonins B (2), C (3), and N (4), and three new analogues, radici...

Like many Americans, especially New Yorkers like me, and probably most readers of Palliative & Supportive Care around the world, I don’t often think about the great state of Montana (aka Big Sky Country) in the Western United States. It usually doesn’t make news, and because it’s ranked 44 in population (about 1 million people) and has very few electoral college votes, it isn’t even one of thos...

In this work, we present a discrete time modeling framework, in which the shape and dynamics of a Limit Order Book (LOB) arise endogenously from an equilibrium between multiple market participants (agents). The new framework captures very closely the true, micro-level, mechanics of an auction-style exchange. At the same time, it uses the standard abstractions of a continuum-player game to obtai...