INTRODUCTION Temozolomide is an alkylating agent approved for treatment of glioblastoma in association with radiotherapy. CASE REPORT We report the case of a 56 year old woman presenting with alveolo-interstitial pneumonia after treatment with Temozolomide. Initially she received induction treatment with Temozolomide and concomitant radiotherapy for bifocal high grade glioblastoma. A month la...

Introduction.-In a series of papers the subject of pneumonia in childhood will be presented mainly from the standpoint of morbid' anatomy and histology, but with reference also to its clinical aspects. Bacteriology will not be dealt with. In the first place, it will be an advantage to obtain a general view of the subject by means of a statistical analysis of a large series of cases, and the pre...

Bovine respiratory disease caused by Mycoplasma bovis is a major health problem of cattle worldwide. It inflicts considerable financial losses on beef herds and is the most common cause of mortality in dairy cattle. Bacteriological examination of 35 nasal cavity samples from calves younger than three months of age identified Mycoplasma bovis in eight (22.9%) samples. These cattle were followed ...

(a) Congenital defects, such as broncho-pleural communication (Folke, 1935), or congenital subpleural vesicles (Kjaergaard, 1932). The pneumothorax may be due to associated anomalies: Miller (1937) recorded a case in which pneumothorax was due to gangrene of the lung resulting from absence of the right pulmonary artery. (b) Mechanical factors: (i) Difficult labour (Ruge, 1878), use of forceps d...

The rarity and importance of such cases as form the basis of this paper, the inadequacy of the study of the similar cases already recorded, and the interesting, though as yet obscure, relationship between an organism or group of organisms which have long been known as actinomyces and the more recently-named streptothricacese, have urged us to the somewhat extended study of our material, which i...

The following study of the bacteriology of pneumonia in infancy was carried on at The Babies' Hospital for several years, with the view of determining the relationship between the extent of the pneu-monic areas and the variety of bacteria present, and the difference, if any, between the bacteriology of the primary and of the secondary infections. Forceps and scalpels were enclosed in sheet iron...

Those who only see whooping-cough in good class practice do not perhaps realise how serious it is liable to be in the children of the poor. The mortality in Edinburgh for a period of five years ending 1900 was '48 per thousand persons living' in fact nearly one-third of the whole zymotic death-rate was caused by this disease. As the children of the better classes rarely succumb to whooping-coug...