Allergic response to common environmental agents has been regarded as a main pathogenetic mechanism of bronchial asthma. However, allergic sensitization (atopy) can not be detected in a siginificant number of adult asthmatic patients. The etiology of nonatopic asthma has not yet been defined. To evaluate the possible involvement of autoimmune response against bronchial mucosa in the pathogenesi...

The aim of this study was to evaluate the effect of bronchial asthma on menstrual cycle. The study population consisted of 111 girls aged 8-17 years (58 girls with bronchial asthma and 53 healthy girls) of the mean age of 13.17+/-2.74 years. The age at menarche and menstrual cycle parameters were analyzed. Asthmatic girls started to menstruate earlier than healthy girls (P=0.0004). The severity...

Aas, K. (1970). Archives of Disease in Childhood, 45, 221. Bronchial provocation tests in asthma. Bronchial provocation tests are necessary for precise aetiological diagnosis in bronchial asthma. This is illustrated by the results in 9,364 bronchial provocation tests compared with skin tests and nasal tests. The technique of bronchial provocation testing and its interpretation are described in ...

Aas, K. (1970). Archives of Disease in Childhood, 45, 221. Bronchial provocation tests in asthma. Bronchial provocation tests are necessary for precise aetiological diagnosis in bronchial asthma. This is illustrated by the results in 9,364 bronchial provocation tests compared with skin tests and nasal tests. The technique of bronchial provocation testing and its interpretation are described in ...

It is not clear whether asymptomatic bronchial responsiveness is a risk factor for development of asthma. A cross-sectional study was conducted to determine the prevalence of asthma among schoolchildren from Barcelona (Spain). The association between respiratory symptoms and bronchial responsiveness to exercise was examined. For this study 3,033 schoolchildren aged 13-14 yrs were studied from t...

Background. The control of severe bronchial asthma, such as corticosteroid-resistant asthma, is difficult. It is also possible that immunosuppressive agents would be effective for bronchial asthma. Case Summary. A 55-year-old Japanese female presented with severe bronchial asthma controlled with tacrolimus. She had been diagnosed with bronchial asthma during childhood. Her asthma worsened, and ...

BACKGROUND Induced sputum in children with bronchial asthma represents a non-invasive method of bronchial inflammation assessment. The main objective of our study was to analyze the cellularity of sputum in patients with bronchial asthma according to the level of disease control and the controlling therapy (with/without inhaled glucocorticoids). The second objective was to establish the correla...

Bronchial thermoplasty is an endoscopic therapy for severe asthma. The previously reported, randomised sham-controlled AIR2 (Asthma Intervention Research 2) trial showed a significant reduction in severe asthma exacerbations, emergency department visits and hospitalisations after bronchial thermoplasty. More "real-world" clinical outcome data is needed.This article compares outcomes in bronchia...

Measurement ofnonspecific bronchial hyperresponsiveness remains largely a research tool in asthma, and its usefulness in the assessment and management of asthma is poorly defined. We StUdied the relationship of bronchial hyperresponsiveness to the clinical severity of asthma in 54 asthmatic subjects. In order to find out whether measurement of bronchial hyperresponsiveness could be used to pred...

Bronchial asthma is assumed to be the result of excessive inflammation driven by an aberrant T-helper-2 (Th2) response. Recently, it has begun to be recognized that asthma is a heterogeneous disorder. Glucocorticoids (GCs) are effective treatment for bronchial asthma; however, the inflammation in bronchial asthma cannot always be fully controlled. A recent study demonstrated a new underlying me...