BACKGROUND Saururus cernuus (Sc) is a small plant, used for the treatment of various human inflammations. The present study aimed at investigating the cytotoxic potential of the methanolic extract of this plant against brine shrimp larvae and human carcinoma cells at normoxic conditions. MATERIALS AND METHODS The in vivo lethality test was evaluated at various doses against brine shrimp larva...

An engineered aquatic ecosystem was specifically designed to bioremediate selenium (Se), occurring as oxidized inorganic selenate from hypersalinized agricultural drainage water while producing brine shrimp enriched in organic Se and omega-3 and omega-6 fatty acids for use in value added nutraceutical food supplements. Selenate was successfully bioremediated by microalgal metabolism into organi...

The new 29-norcucurbitacin, desacetylfevicordin A (1), together with three known 29-norcucurbitacin derivatives (2-4) were isolated from seeds of the Indonesian medicinal plant, Phaleria macrocarpa (Scheff.) Boerl. The structures of 1-4 were elucidated on the basis of spectroscopic analyses and chemical transformation. These compounds exhibited toxicity against the brine shrimp (Artemia salina).

Purpose: To determine, in Sprague Dawley rats, the toxicity profile of the methanol extract of Mentha spicata, a plant used in folklore medicine for the treatment of various forms of pain. Methods: The plant extract, at concentrations ranging from 100 0.07 mg/ml, was used to determine the median lethal concentration (LC50) based on brine shrimp lethality assay. Artificial sea water served as co...

the composition of the essential oil from the stalks and flowers of rheum ribes l., growing in iran, were extracted by hydrodistillation and analyzed by gc-ms. thirty constituents representing 93.84% of rheum oil were identified.  the oil was found to be rich in hydrocarbons especially long-chain n-alkanes (80.81%). the most abundant components in the oil included tricosane (26.29%), heneicosan...

Amalakyadi churna is an Ayurvedic formulation, which is extensively used in traditional system of Indian medicine and by folk practitioner for treating all types of fever, and other common ailments In this study, an equal concentration of ethanolic extracts of Amalakyadi churna and its ingredients (50μg/ml of artificial sea water) were subjected to a bioscreening study to detect the cytotoxic a...

The methanol extract of Cassia fistula seeds was investigated for potential antimicrobial activity against medically important bacterial, yeast and fungal strains. The antimicrobial activity was determined in methanol extract using the disk diffusion technique and the broth dilution method. The extract was effective on tested microorganism and the minimum inhibitory concentration (MIC) values w...

BACKGROUND Diabetes mellitus is a chronic metabolic disease with life-threatening complications. Despite the enormous progress in conventional medicine and pharmaceutical industry, herbal-based medicines are still a common practice for the treatment of diabetes. This study evaluated ethanolic and aqueous extracts of selected Sudanese plants that are traditionally used to treat diabetes. METHO...

in the present study, aqueous solutions of some copper-complexing ligands were screened for their cytotoxicity using brine shrimp lethality test. among the ligands tested, diacetyl-bis(n4-methylthiosemicarbazones) (atsm) proved to be the most safe and non-toxic compound (2% lethality at 10 ppm), while pyruvaldehyde bis(n4-methyl)thiosemicarbazone (ptsm) was shown to possess low toxicity (7% let...

Cinnamomum species have long been used as spices. The preliminary bioactive constituent’s identification and brine shrimp lethality activities of ethanolic extracts of seven Cinnamomum species viz., C. travancoricum, C. walaiwarense, C. wightii, C. verum, C. sulphuratum, C. riparium, and C. perrottetii were evaluated in this study. The results of cytotoxic activity of the bark extracts of seven...