Deficits on two continuous performance test versions and the forced-choice span of apprehension task, which are potential vulnerability factors for schizophrenic disorders, were examined in relationship to particular symptoms of schizophrenic disorders, with emphasis on hypothesized relationships to formal thought disorder and negative symptoms. These interrelationships were determined concurre...

BACKGROUND Differential effects of genes and environment can contribute to etiological heterogeneity in schizophrenia. Twins concordant and discordant for schizophrenia may differ in genetic predisposition to schizophrenia with concordant twins having a higher genetic liability and discordant twins having a lower genetic liability to schizophrenia. We aimed to investigate whether P300 amplitude...

BACKGROUND Improvements are greatest in the earlier weeks of antipsychotic treatment of patients with non-resistant schizophrenia. AIMS To address the early time-line for improvement with antipsychotics in treatment-resistant schizophrenia. METHOD Randomised double-blind trials of antipsychotic medication in adult patients with treatment-resistant schizophrenia were investigated (last searc...

AIM The aim of the study was the assessment of types and incidence of aggressive behaviours amongst psychiatric patients with violent acts marked in the referrals. METHODS 107 patients with aggressive or autoaggressive behaviours admitted to the General Hospital of Mental Disorders in Lubiaz and 37 controls without aggressive acts in referrals were examined. Two-way data analysis of the quali...

We investigated the validity of expressed emotion (EE) in Israel. The study sample consisted of 108 patients with schizophrenia and 15 with schizoaffective disorder, and their key relatives. EE was rated with the Five Minute Speech Sample (FMSS). Patient households were categorized by EE and its two components: criticism and emotional overinvolvement. Patients were rated with the Brief Psychiat...

Factor analytic work on the Positive and Negative Syndrome Scale (PANSS) and Brief Psychiatric Rating Scale (BPRS) has yielded varied and conflicting results. The current study explored potential causes of these discrepancies. Prior research has been limited by small sample sizes and an incorrect assumption that the items are normally distributed when in practice responses are highly skewed ord...

impact of psychoeducational groups for caregivers on the psychiatric symptoms of patients with schizophrenia     shaygan m [1] *, sharif f [2]     received: 21 nov, 2012 accepted: 11 feb , 2013     abstract:   background & aims : schizophrenia is a severe psychiatric disorder, which is extremely stressful not only for the persons affected but also for their families.   materials & methods : to ...

Objective The aim of the current study was to evaluate whether cognitive behavioral group therapy has a positive impact on psychiatric, and motor and non-motor symptoms in Parkinson's disease (PD). Methods We assigned 20 PD patients with a diagnosis of psychiatric disorder to either a 12-week cognitive behavioral therapy (CBT) group or a psychoeducational protocol. For the neurological examin...

OBJECTIVES The pharmacotherapy of Parkinson's disease (PD) is often challenging as clinicians have to find a favourable balance between the efficacy on motor symptoms and side effect profiles of different dopaminergic medications. We aimed to assess the available evidence on the role of dopamine agonist monotherapy as an alternative to Levodopa in the treatment of motor symptoms of PD, along wi...