PURPOSE Novel radiotracers could potentially allow the identification of clinically aggressive tumor phenotypes. As choline metabolism increases during malignant transformation and progression of human mammary epithelial cells, we examined the ability of [(11)C]choline (CHO) positron emission tomography imaging to detect clinically aggressive phenotype in patients with estrogen receptor (ER)-po...

OBJECTIVE The aim was to determine what effect the offer of a cervical smear test when attending for breast screening has on the uptake of cervical and breast screening. DESIGN The study involved randomisation to compare uptake in those women invited for cervical screening in advance with their breast screening invitation (group 1) with those invited for breast screening only and then offered...

BACKGROUND A number of studies have reported low uptake of cancer screening programmes by South Asian populations in the UK. However, studies to date have not adjusted findings for differences in demographics and socio-economic status of these populations. METHODS SUBJECTS All residents in Coventry and Warwickshire, UK, eligible for screening. Uptakes compared for round 1 (2000-02) and rou...

Fructose transporter GLUT5 is overexpressed in breast cancer cell lines, but not in healthy tissue. Micelles based on fructose, which were found to be low fouling, showed a high uptake by breast cancer cells (MCF-7 and MDA-MB-231 cells), but only negligible uptake by macrophages.

I-131 uptake in the breast has been described with a variety of normal and pathologic conditions. We present the case of a 38-year-old female who received 317 millicuries of radioactive I-131 treatment for papillary thyroid carcinoma. Post-treatment scan demonstrated I-131 uptake in an area of fat necrosis in the breast.

Download pose: This study sought to evaluate the reproducibility of [C]choline-positron emission tomogand the effect of trastuzumab in breast cancer. erimental Design: Twenty-one patients with newly diagnosed and recurrent breast cancer stage IIa baseline dynamic [C]choline-PET scan, 10 patients had a second [C]choline-PET scan to ne reproducibility, and 6 patients had a second scan within a mo...

Whether or not U.S. women follow the recommended breast cancer screening guidelines is related to the perceived benefits and harms of the procedure. Twitter is a rich source of subjective information containing individuals’ sentiment towards public health interventions/technologies. Using a modified version of Hutto and Gilbert (2014) sentiment classifier, we described the temporal, geospatial,...

L-[methyl-"1C]methionine ("IC-methionine) uptake of seven primary breast cancers, four soft tissue metastases of breast cancer, and three other breast lesions was studied by positron emission tomography (PET). "C-methionine accumulation was assessed by calculating the standardised uptake value (SUV). The mean SUV for breast cancer was 8.5± 3.3 (s.d.), while the maximal uptake in the liver was 1...

The objective of the study was to characterize pale breast meat, compare it with normal colored breast meat, and determine whether it should be considered pale, soft, and exudative (PSE). Characteristics of 20 normal and 20 pale broiler breasts, obtained at a commercial slaughter plant, were evaluated. Compared with normal meat, the pale breast meat had a significantly (P < 0.05) lower pH (5.7 ...

Introduction: A main choice for cancer treatment is radiotherapy. But, the radiotherapy disadvantage is damages caused by radiation given to normal tissues/organs surrounding cancer. One way to avoid this is via increasing radiosensitization of cancer cells. Gold nanoparticles (GNPs) have shown sensitizing effect on cancer cells by enhancing their absorbed dose. Unlike earlier ...