Background: The heterogeneous breast cancer is the most common cause of cancer-related mortality. Obesity defined by BMI is known as a major risk factor for breast cancer. Objective: The purpose of this study was to explore the role of obesity related-polymorphisms rs9939609 FTO and rs17782313 MC4R in breast cancer development. Materials and Methods: We obtained matched peripheral blood, serum ...

background: the etiology of breast cancer and our understanding on the carcinogenicity of different risk factors is impotant for control programms. objective: we investigated the expression of estrogen and progesterone receptors (er, pr), and human epithelial receptor 2 (her2) overexpression and its associations, with environmental risk factors among breast cancer patients.  methods: we classif...

background: in some verses in holy quran; 233 surat al-baghare , 15 al-ahghaf , 14 loghman and 6 al-talagh, breastfeeding, gravidity, and parity recommended to the parents and expected their children to be accountable to the parents; particularly to mothers due to tolerate of pregnancy and breastfeeding duration. methods: the case-control study included 376 patients diagnosed between      2001-...

  Abstract   Background: Due to the high incidence of breast cancer and the effect of its early   diagnosis on decreasing morbidity and mortality, we used the Gail model to study   breast cancer risk in Iranian women.   Methods: This study was done in a simple randomized way. Participants were 2000   Iranian women older than 35 years old. The questionnaire consisted of demographic   data such a...

breast cancer affects iranian women at least one decade younger than their counterparts in othercountries and the incidence of breast fibroadenoma is growing in the last two decades in tehran. thisstudy aimed to compare the ahr levels in premenopausal breast cancer and breast fibroadnemo withappropriate normal groups. possible associations of ahr with lifestyle and reproductive risk factorsand ...

To establish a comprehensive picture of the relationship between glutathione S-transferase omega 2 (GSTO2; MIM: 612314) gene N142D variant (rs. 156697) and breast cancer risk, the present meta-analysis was carried out. Studies published up to July 2012 with information about GSTO2 polymorphism and breast cancer risk were identified using several electronic databases. We identified 4 eligible st...

Background: Large part of research related to reproductive factors in breast cancer risk before and after menopause, a study case - control is that it factors in deliberate and spontaneous abortion in the two groups of women with breast cancer (cases) and non-infected women (control group) study, described odds ratio in women, breast cancer was measured. In this study, after recognizing the abo...

Background & aim: Evaluation of prevalence of risk factors for breast cancer in different regions of Iran and identification of their significant effect on this disease can promote the prevention and reduction of breast cancer incidence. Therefore, this study aimed to evaluate the prevalence, demographic characteristics, and frequency of the risk factors of breast cancer during 10 years. Method...

background: one of the economic evaluation techniques involves calculation of willingness to pay (wtp) for a service to find out the value of that service from the clients’ perspective. this study estimated wtp for both breast cancer and osteoporosis screening and comparatively examined the contributing factors. in fact, the comparisons served to provide an exact analysis of individual attitude...

The fact that the development of breast cancer is linked to repeated or sustained exposure to high blood estrogen levels has raised obvious concern that reproductive hormones particularly estrogen, might increase the risk of breast cancer development. While, the general consensus is that overall; IVF is not associated with an increased risk for development of breast cancer, a recent report publ...