background : magnetic resonance imaging (mri) offers higher diagnostic accuracy for brain lesions caused by heroin abuse compared to compute tomography (ct) scan. these lesions have a low signal on t1-weighted (t1w) images and a high signal on t2-weighted (t2w) and fluid-attenuated inversion recovery (flair) images. this study aimed to evaluate the role of diffusion-weighted mri (dwi-mri) in he...

this study was conducted to find out the best outside points of skull to reach different areas of brain thatare essential for neuroendocrinological studies. in this research 30 heads of iranian native male goats agedbetween 2-3-year-old were collected from shahrekord abattoir. after collecting whole heads, they were fixedin 10% formalin and then many holes were made on the dorsal surface of sku...

two physicians, both grown up in west europe, educated also in this area (supplemented by many visits of the united states), travelled 20 years ago to japan for scientific reasons and they changed thereafter in their mental sight of the world. in a first part, the neurophysiologic basis of sensation from the sensory receptor up to the cerebral cortex (“bottom up”), the mechanisms of building me...

neuroinflamation occurring after traumatic brain injury (tbi) is a complex phenomenon comprising distinct cellular and molecular events involving the injured cerebral tissue. mechanical injury to adult rat brain elucidated the accumulation in the affected area of trophic activity. in the tissue adjacent to the injury, trophic titers began to rise after the lesion. this study aimed to determine ...

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in the mammalian, there are three ncx genes (ncx1, ncx2, ncx3), which their three proteins are differentially expressed in distinct regions of the central nervous system, where they might underlie different physiological and pathophysiological functions. ncx is a nine-transmembrane protein which is distributed in the brain widely. ncx operates in a bidirectional way, and exchanges ca2+ and na+ ...

conclusions increased serum levels of interleukins 6 and 8 as a predictive marker might be associated with unfavorable clinical outcome in patients with severe tbi. results comparing the serum levels of interleukins in two groups with favorable and unfavorable clinical outcomes showed that the mean serum levels of interleukins 6 and 8 in group with favorable outcome was 85.2 ± 51.6 and 52.2 ± 3...

nowadays brain tumors remain as a significant cause of morbidity and mortality and are often treatment refractory. the grading of brain tumor has an important implication in clinical management. currently, magnetic resonance spectroscopy (mrs) is an important modality in evaluating and grading brain tumors. the aim of this study is  evaluation of metabolites in the differentiation of brain tumo...

naturally the brain is ineffective in regenerating functional tissue after disease or injury, so to overcome these defects innovative curative strategies such as stem cell transplantation and tissue engineering have to be considered. researchers investigate the use of strategies to attain better functional repair results. one of the important challenges of effective transplantation is the deliv...