OBJECTIVE To evaluate the association of the V249I and T280M variants of CX3CR1 fractalkine gene with carotid intima-media thickness in Mexican subjects with and without type 2 diabetes. METHODS We analyzed the V249I and T280M variants of the CX3CR1 receptor by TaqMan assays in 111 subjects with type 2 diabetes and 109 healthy controls. Hemoglobin A1c, glucose, and lipid profile were determin...

BACKGROUND The aim of this study was to assess the relationship between brachial artery flow mediated dilation (FMD), carotid artery intima-media thickness (IMT) and coronary flow reserve (CFR) in patients with coronary artery disease (CAD). METHODS Fifty patients with coronary artery disease, except left anterior descending artery (LAD), who showed no cardiac symptoms and 45 control subjects...

Introduction Endothelial function at high altitude has been measured only in populations that are genetically adapted to chronic hypoxia. The objective of this study was to evaluate endothelial dysfunction (ED) in a nongenetically adapted high-altitude population of the Andes mountains, in Huancayo, Peru (3,250 meters above sea level). Methods Participants included 61 patients: 28 cases and 3...

Introduction:Due to increase in Coronary Artery Disease (CAD) at a younger age, we should try diagnose atherosclerotic process and population risk, the earliest. Flow Mediated Dilatation (FMD), Carotid Intima-Media Thickness (CIMT) Ankle-Brachial Pressure Index (ABI) are probable markers for early atherosclerosis may be useful coronary risk stratification Objectives: To compare correlate FMD, C...

Pregnancy and childbirth are associated with hemodynamic changes and vascular remodeling. It is not known whether parity is associated with later adverse vascular properties such as larger arterial diameter, wall thickness, and lower distensibility. We used baseline data from 3283 women free of cardiovascular disease aged 45 to 84 years enrolled in the population-based Multi-Ethnic Study of Ath...

background: common carotid intima-media thickness (cc-imt) measured by ultrasonography as a non-invasive method is nowadays known as a marker for early atherosclerosis. objectives: survey the relationship between serum uric acid and carotid intima-media thickness considering hypertension. materials and methods: this study was designed as a comparative cross-sectional study in northern iran in 2...

OBJECTIVE Obesity is an established risk factor for cardiovascular disease. The mechanisms by which obesity affects cardiovascular risk have not been fully elucidated. This paper reports a comprehensive systematic review and meta-analysis on obesity and two key aspects of vascular health using gold-standard non-invasive measures - arterial endothelial function (brachial flow-mediated dilatation...

background the behcet disease is a multisystemic disease with involvement of vessels. objectives our aim is to evaluate the frequency of carotid artery disease in asymptomatic carotid artery involvement in patients with behcet disease and compare the results with a control group. patients and methods fifty patients with behcet disease who were asymptomatic for any vascular involvement and 50 he...

1. Repeatability of measurements of arterial compliance and flow-mediated dilation of the brachial artery has been infrequently reported, despite increasing use in interventional and risk-factor modification studies. Furthermore, little is known about the interrelationships of the various indices. The purposes of this study were to determine the repeatability and interrelationships of a range o...

endothelial dysfunction and carotid intima-media thickness are 2 indicators of subclinical cardiovascular disease. the aim of study was to analyze brachial flow mediated dilation(fmd)and carotid intima media thickness (cimt)in patients with coronary artery disease, and investigate the relationship between endothelial function, cimt and coronary artery disease risk factors.56 men and women aged ...