Introduction Endothelial function at high altitude has been measured only in populations that are genetically adapted to chronic hypoxia. The objective of this study was to evaluate endothelial dysfunction (ED) in a nongenetically adapted high-altitude population of the Andes mountains, in Huancayo, Peru (3,250 meters above sea level). Methods Participants included 61 patients: 28 cases and 3...

background: common carotid arterial stiffness can be assessed during carotid arterial ultrasonography, but its association with brachial stiffness, a well-defined cardiovascular risk factor, has not been clarified. the aim of this study was to examine the relationship between common carotid artery and brachial artery stiffness. methods: the static pressure-strain elastic modulus of the common c...

Variations in arterial anatomy are less frequent, contrary to the venous system, and most of these variations affect visceral arteries. Variations in the brachial artery are the most frequently reported and so far a minimum of six different patterns have been described. The most common of these patterns is the superficial brachial artery, which lies superficially to the medi...

OBJECTIVES We evaluated the potential vasodilator effects of transcutaneous low-frequency ultrasound (US) in human brachial arteries. BACKGROUND Recent data show that transthoracic low-frequency US energy results in canine coronary artery vasodilation. METHODS Brachial artery diameters were measured before and after low-frequency US (29 kHz, 1.4 W/cm2) exposure using US imaging with a linea...

We performed simultaneous noninvasive measurements of common carotid artery and brachial artery hemodynamics in nine normal subjects and 10 subjects with sustained essential hypertension. In hypertensive subjects, brachial artery blood flow and forearm vascular resistance were in the normal range while carotid artery blood flow and carotid artery resistance were decreased and increased, respect...

BACKGROUND Epidemiological studies indicate that estrogen replacement therapy decreases the risk of cardiovascular events in postmenopausal women. Estrogen may confer cardiovascular protection by improving endothelial function because it increases endothelium-dependent vasodilation. It is not known whether progesterone attenuates the beneficial effects of estrogen on endothelial function. MET...

BACKGROUND Impaired arterial dilatation response to nitroglycerin has been observed in adults with risk factors for atherosclerosis and in patients with established atherosclerotic disease. This defect parallels changes in vascular endothelial function and may be attributed to increased oxidative stress. Because atherosclerosis begins in childhood, we examined the correlates of nitrate-mediated...

In an open prospective phase-IV pilot study the effect of selenium (intravenous bolus injection of 500μg sodium selenite) was investigated on the brachial artery diameter of patients (n=20) with peripheral arterial occlusive disease in stage II according to Fontaine (PAODII) and selenium deficiency. Flow-mediated vasodilation was assessed under resting conditions (control phase) and at 5 and 30...

Methods and Results-—Thirteen healthy young (23 2 years) and 13 older men (61 5 years) were instructed to continuously wear a compression sleeve around the right forearm to chronically (2 weeks) elevate brachial artery retrograde SR in 1 arm. We assessed SR, diameter, and flow-mediated dilation in both the sleeve and contralateral control arms at baseline and after 30 minutes and 2 weeks of con...